NKG7 and TMEM88

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NKG7	TMEM88
Description		natural killer cell granule protein 7	transmembrane protein 88
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Membrane Cytolytic Granule Cytolytic Granule Membrane	Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding
	Biological Process	Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Inflammatory Response Killing Of Cells Of Another Organism CD4-positive, Alpha-beta T Cell Activation Natural Killer Cell Mediated Cytotoxicity Defense Response To Protozoan Natural Killer Cell Degranulation Positive Regulation Of Inflammatory Response Granzyme-mediated Programmed Cell Death Signaling Pathway	Wnt Signaling Pathway Protein Stabilization Protein Localization To Plasma Membrane Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		49 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM209A FAM210B FFAR2 FKBP7 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC10A1 SLC18A2 SLC30A8 SLC35H1 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	9 interacting genes: GYPC MFF NKG7 TIMM23 TMEM11 TMEM218 TMEM50B VRK2 ZDHHC22
Entrez ID		4818	92162
HPRD ID		16188	17438
Ensembl ID		ENSG00000105374	ENSG00000167874
Uniprot IDs		A0A0B4J2A6 Q16617	I3L2J3 Q6PEY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding	Protein Targeting Protein Targeting To Mitochondrion Membrane Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Organelle Envelope Establishment Of Protein Localization To Mitochondrion
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