NKG7 and MSR1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		NKG7	MSR1
Description		natural killer cell granule protein 7	macrophage scavenger receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Membrane Cytolytic Granule Cytolytic Granule Membrane	Collagen Trimer Plasma Membrane Membrane Endocytic Vesicle Membrane Low-density Lipoprotein Particle
	Molecular Function	Protein Binding	Amyloid-beta Binding Scavenger Receptor Activity Protein Binding Low-density Lipoprotein Particle Binding Cargo Receptor Activity
	Biological Process	Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Inflammatory Response Killing Of Cells Of Another Organism CD4-positive, Alpha-beta T Cell Activation Natural Killer Cell Mediated Cytotoxicity Defense Response To Protozoan Natural Killer Cell Degranulation Positive Regulation Of Inflammatory Response Granzyme-mediated Programmed Cell Death Signaling Pathway	Endocytosis Receptor-mediated Endocytosis Phagocytosis, Engulfment Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Storage Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Transport Establishment Of Localization In Cell Amyloid-beta Clearance
Pathways			Scavenging by Class A Receptors Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494)	Alcohol dependence ( 26365420) Blood protein levels ( 23696881) HDL cholesterol levels in HIV infection ( 33109212) Hip circumference adjusted for BMI ( 28552196) Neurological blood protein biomarker levels ( 31320639) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		49 interacting genes: AGTRAP AMIGO1 AQP6 ARL13B ATP6AP2 BAMBI CD53 CD79A CLDN7 CLEC2D CLEC4E CLSTN3 CREB3 EBP EDA2R ERGIC3 FAM209A FAM210B FFAR2 FKBP7 FNDC9 GJA5 GORAB GPX8 ISLR2 KLRC1 LHFPL5 LMNA MFSD6 MGST3 MS4A3 MSR1 MUC1 OPRK1 PEX12 RAMP1 RNF24 SLC10A1 SLC18A2 SLC30A8 SLC35H1 STOM STX1A TLCD4 TMEM106C TMEM130 TMEM139 TMEM80 TMEM88	9 interacting genes: ADRB2 ATP6V0C FA2H HSPA1A LEPROTL1 MALL NKG7 SEC22A SNCA
Entrez ID		4818	4481
HPRD ID		16188	01092
Ensembl ID		ENSG00000105374	ENSG00000038945
Uniprot IDs		A0A0B4J2A6 Q16617	B4DDJ5 P21757
PDB IDs			7DPX
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Protein Binding	Establishment Of Localization In Cell Inclusion Body Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Vesicle-mediated Transport Vacuolar Transport Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Microtubule Polymerization Membrane Organization Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission 4-hydroxysphinganine Ceramide Fatty Acyl 2-hydroxylase Activity Free Fatty Acid 2-hydroxylase Activity Fatty Acid 2-hydroxylase Activity Enzyme Binding Regulation Of Autophagy Beta2-adrenergic Receptor Activity Denatured Protein Binding Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Sebaceous Gland Cell Differentiation Glucosylceramide Biosynthetic Process Regulation Of Sebum Secreting Cell Proliferation Regulation Of Acinar Cell Proliferation Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Mitochondrial Membrane Organization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Defense Response Regulated Exocytosis Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Central Nervous System Myelin Maintenance Lysosome Norepinephrine Binding Lysosomal Transport Positive Regulation Of Organelle Organization Intracellular Transport Synaptic Vesicle Membrane Death Receptor Agonist Activity Cytolytic Granule Membrane Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Response To Psychosocial Stress
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?