CD5 and DYNLT3

Number of citations: 0 (PubMedID 9692886)
Data Source: HPRD (two hybrid)

		CD5	DYNLT3
Name		CD5 molecule	dynein light chain Tctex-type 3
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Chromosome, Centromeric Region Kinetochore Nucleus Chromosome Cytoplasm Cytoskeleton Cytoplasmic Dynein Complex Microtubule Dynein Complex Mitotic Spindle Astral Microtubule
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Cell Recognition T Cell Costimulation Apoptotic Signaling Pathway	Microtubule-based Movement Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division
GWAS		Coffee consumption ( 31046077 ) Gut microbiota (bacterial taxa) ( 27694959 ) Gut microbiota (functional units) ( 27694959 ) Inflammatory bowel disease ( 23128233 ) Multiple sclerosis ( 21833088 24076602 ) Rheumatoid arthritis ( 23143596 24390342 30423114 ) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676 ) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 ) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 )	No GWAS studies recorded
Interacting Genes		21 interacting genes: CAMK2D CBL CD2 CD247 CD4 CD6 CD72 CD79A CD79B CSNK2A1 DYNLT3 FYN HNRNPU LCK PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70	11 interacting genes: C2orf15 CCL28 CD5 DYNC1I1 DYNC1I2 NIF3L1 PMS1 PVR TESC VDAC1 ZC3H14
Entrez ID		921	6990
HPRD ID		01078	02249
Ensembl ID		ENSG00000110448	ENSG00000165169
Uniprot IDs		P06127	P51808
PDB IDs		2JA4 2JOP 2JP0 2OTT	Not available
GO Terms Enriched among Interactors		Cell Surface Receptor Signaling Pathway Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Phosphotyrosine Residue Binding Plasma Membrane Leukocyte Activation Signal Transduction Positive Regulation Of Immune System Process Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Activation Adaptive Immune Response Regulation Of Immune System Process T Cell Receptor Complex B Cell Receptor Signaling Pathway Cell-cell Junction Immune Response-activating Signaling Pathway Immune Response Regulation Of Immune Response Signaling Receptor Binding Immune System Process Immune Response-regulating Signaling Pathway Activation Of Immune Response Regulation Of Cell Adhesion Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Immune Response Regulation Of Apoptotic Process Protein Kinase Activity Identical Protein Binding T Cell Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Programmed Cell Death Protein Phosphorylation Intracellular Signal Transduction Membrane Raft Peptidyl-tyrosine Phosphorylation Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Lymphocyte Differentiation Phosphatidylinositol 3-kinase Binding Histone H3T6 Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of T Cell Activation Kinase Activity Regulation Of Hemopoiesis Negative Regulation Of Apoptotic Process Positive Regulation Of Leukocyte Cell-cell Adhesion	Dynein Light Chain Binding Dynein Heavy Chain Binding Cytoplasmic Dynein Complex