DYNLT3 and PVR

Number of citations of the paper that reports this interaction (PMID 11751937)
22

Data Source:
HPRD (in vivo)

		DYNLT3	PVR
Gene Name		dynein, light chain, Tctex-type 3	poliovirus receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasmic Dynein Complex Microtubule	Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Identical Protein Binding	Virus Receptor Activity Receptor Activity Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Transport Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Metabolic Process Cell Division	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Virus Viral Process Single Organismal Cell-cell Adhesion Cell Migration Cell Junction Assembly Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell-cell Junction Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity
Pathways			Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		7 interactors: CD5 DYNC1I1 DYNC1I2 NIF3L1 PVR TESC VDAC1	18 interactors: AP1M2 CD226 CD96 DYNLT1 DYNLT3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NOTCH2NL PLA2G3 PVRL1 PVRL3 SLC30A2 TIGIT TNFRSF12A VTN WNK1
Entrez ID		6990	5817
HPRD ID		02249	01434
Ensembl ID		ENSG00000165169	ENSG00000073008
Uniprot IDs		P51808 Q6ICS3	P15151
PDB IDs			1DGI 1NN8 3EPC 3EPD 3EPF 3UDW 3URO 4FQP
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Viral Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Susceptibility To T Cell Mediated Cytotoxicity 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Positive Regulation Of Sodium:proton Antiporter Activity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune System Process Immune System Process Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Antigen Processing And Presentation Microtubule-based Movement Regulation Of Proton Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Immune System Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Megakaryocyte Differentiation Transport Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Ion Transmembrane Transport Megakaryocyte Differentiation Regulation Of Natural Killer Cell Mediated Cytotoxicity Movement Of Cell Or Subcellular Component Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Sodium Ion Transmembrane Transporter Activity	Cell Adhesion Lens Morphogenesis In Camera-type Eye Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Immune System Process Positive Regulation Of Sequestering Of Zinc Ion Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Adherens Junction Organization Lens Development In Camera-type Eye Anatomical Structure Morphogenesis Cell Differentiation Interaction With Host Organelle Localization Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Substrate-dependent Cell Migration, Cell Attachment To Substrate Regulation Of Wound Healing Camera-type Eye Morphogenesis Negative Regulation Of Pancreatic Juice Secretion Intracellular Transport Of Viral Protein In Host Cell Transport Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Viral Process Eye Morphogenesis Retina Development In Camera-type Eye Enamel Mineralization Positive Regulation Of Immune Response To Tumor Cell Immune Response Viral Life Cycle Developmental Process Immune System Process Cell Junction Assembly Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Sperm Axoneme Assembly Tooth Mineralization Cell-cell Junction Organization Cell-substrate Adhesion Positive Regulation Of Systemic Arterial Blood Pressure Lipoxygenase Pathway Desmosome Organization Cell Adhesion Mediated By Integrin Positive Regulation Of Mast Cell Activation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Phosphatidylglycerol Acyl-chain Remodeling Acrosome Assembly Amelogenesis Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Tagcloud ?		associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60	advance catheterization collaborative consensus epoprostenol glaxo hemodynamic investigators mailed multicenter nc nineteen optimize output page pap park pph pulmonary responded routinely scheduled survey thirds triangle unresponsive vasodilator wellcome worsening
Tagcloud (Difference) ?		associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60	advance catheterization collaborative consensus epoprostenol glaxo hemodynamic investigators mailed multicenter nc nineteen optimize output page pap park pph pulmonary responded routinely scheduled survey thirds triangle unresponsive vasodilator wellcome worsening
Tagcloud (Intersection) ?