CD5 and PRKCG

Number of citations of the paper that reports this interaction (PMID 11123317)
2

Data Source:
HPRD (in vitro)

		CD5	PRKCG
Gene Name		CD5 molecule	protein kinase C, gamma
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Nucleus Cytosol Plasma Membrane Cell-cell Junction Dendrite Perinuclear Region Of Cytoplasm Synaptic Membrane
	Molecular Function	Receptor Activity Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding	Protein Kinase Activity Protein Kinase C Activity Calcium-dependent Protein Kinase C Activity Protein Serine/threonine/tyrosine Kinase Activity ATP Binding Zinc Ion Binding
	Biological Process	Receptor-mediated Endocytosis Cell Recognition Cell Proliferation T Cell Costimulation Apoptotic Signaling Pathway	Protein Phosphorylation Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Activation Of Phospholipase C Activity Synaptic Transmission Blood Coagulation Learning Or Memory Chemosensory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Phosphorylation Platelet Activation Negative Regulation Of Protein Ubiquitination Regulation Of Response To Food Positive Regulation Of Mismatch Repair Intracellular Signal Transduction Negative Regulation Of Protein Catabolic Process Regulation Of Circadian Rhythm Response To Morphine Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Protein Autophosphorylation Neurotrophin TRK Receptor Signaling Pathway Response To Pain Rhythmic Process Innervation Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways			Signaling by GPCR Ca-dependent events CaM pathway Phospholipase C-mediated cascade Signaling by FGFR in disease Signaling by Wnt Signaling by EGFRvIII in Cancer PLCG1 events in ERBB2 signaling DAP12 signaling Response to elevated platelet cytosolic Ca2+ G alpha (z) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Signaling by PDGF Calmodulin induced events DAP12 interactions Opioid Signalling EGFR interacts with phospholipase C-gamma Signaling by ERBB2 Signaling by EGFR GPCR downstream signaling Downstream signal transduction Calmodulin induced events WNT5A-dependent internalization of FZD4 Signaling by EGFR in Cancer Platelet activation, signaling and aggregation PCP/CE pathway Transmission across Chemical Synapses Trafficking of GluR2-containing AMPA receptors DAG and IP3 signaling CaM pathway Downstream signaling of activated FGFR Disinhibition of SNARE formation Innate Immune System Signalling by NGF PLC beta mediated events Signaling by Ligand-Responsive EGFR Variants in Cancer G-protein mediated events NGF signalling via TRKA from the plasma membrane Trafficking of AMPA receptors Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR beta-catenin independent WNT signaling PLC-gamma1 signalling Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088)
Protein-Protein Interactions		22 interactors: CAMK2D CBL CD2 CD247 CD27 CD4 CD6 CD72 CD79A CD79B CSNK2A1 DYNLT3 FYN HNRNPU LCK PIK3R1 PRKCA PRKCB PRKCG PTPN6 RASA1 ZAP70	58 interactors: ADRBK1 AFAP1 ANXA7 APP ARHGEF25 CASR CCHCR1 CD5 CDC42 CHAT CYTH2 DAB2 DDX58 DVL2 EIF4E EPHB1 EXOC5 GABRA1 GABRA4 GFAP GJA1 GJA3 GRIA4 GRIN1 GRIN2B GRIN2D GRM5 GSK3A HABP4 HSPA4 IRS1 ITGB2 MARK4 NFE2L2 NOXA1 NRGN NUMB PA2G4 PARD3 PARD6A PARD6B PDLIM5 PEBP1 PICK1 PNMA1 PPP1R14A RANBP10 RGS2 SCN3A SDC2 STXBP1 TIAM1 TOP2A TRIM5 VTN YWHAB YWHAE YWHAG
Entrez ID		921	5582
HPRD ID		01078	01502
Ensembl ID		ENSG00000110448	ENSG00000126583
Uniprot IDs		P06127	F5H5C4 P05129
PDB IDs		2JA4 2JOP 2JP0 2OTT	2E73 2UZP
Enriched GO Terms of Interacting Partners?		Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Cell Activation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Immune System Process Regulation Of Lymphocyte Activation Regulation Of Cell Adhesion T Cell Costimulation Positive Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Signal Transduction B Cell Receptor Signaling Pathway Immune Response Signal Transduction Platelet Activation Positive Regulation Of T Cell Activation T Cell Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Adhesion Innate Immune Response Signaling Leukocyte Migration Cell Communication Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Immune Response Blood Coagulation Hemostasis Locomotion Leukocyte Activation Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Defense Response To Virus By Virus Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Stimulus Response To Fibroblast Growth Factor Movement Of Cell Or Subcellular Component Protein Autophosphorylation Regulation Of Body Fluid Levels	Regulation Of Signaling Regulation Of Cellular Process Signaling Nervous System Development Cell Communication Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Developmental Process Anatomical Structure Development Generation Of Neurons System Development Neuron Development Neuron Projection Development Neurogenesis Signal Transduction Positive Regulation Of Transport Regulation Of Cellular Component Organization Cell Differentiation Response To Stimulus Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Regulation Of Signal Transduction Cell Projection Organization Cellular Response To Stimulus Axon Development Glutamate Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Involved In Neuron Differentiation Enzyme Linked Receptor Protein Signaling Pathway Response To Stress Cell-cell Signaling Response To Organic Substance Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Catalytic Activity Cell Projection Morphogenesis Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Metabolic Process Cell Part Morphogenesis Ephrin Receptor Signaling Pathway Regulation Of Cellular Localization Cell Morphogenesis Regulation Of Synaptic Plasticity Axon Guidance Positive Regulation Of Catalytic Activity Neuron-neuron Synaptic Transmission Transport Regulation Of Cell Development
Tagcloud ?		bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd psg1 pw39 tnnt1
Tagcloud (Difference) ?		bmt cd11b cd11c cd19 cd45 cytometric cytopenias deferral definitive dilemma gating hairy hcl hodgkin immunophenotyping maturing mdf morphologic multidimensional myeloblast myelodysplasia pancytopenia phenotyping presumptive refined reside scatter scheme unexplained	apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd psg1 pw39 tnnt1
Tagcloud (Intersection) ?