DYNLT3 and VDAC1

Number of citations of the paper that reports this interaction (PubMedID 12009301)
0

Data Source:
HPRD (two hybrid, in vitro)

		DYNLT3	VDAC1
Description		dynein light chain Tctex-type 3	voltage dependent anion channel 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Chromosome Cytoplasm Cytoskeleton Cytoplasmic Dynein Complex Microtubule Dynein Complex Mitotic Spindle Astral Microtubule	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Membrane Mitochondrial Nucleoid Membrane Raft Synapse Pore Complex Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Nucleotide Binding Voltage-gated Monoatomic Ion Channel Activity Protein Binding ATP Binding Oxysterol Binding Lipid Binding Voltage-gated Monoatomic Anion Channel Activity Porin Activity Cholesterol Binding Protein Kinase Binding Phosphatidylcholine Binding Identical Protein Binding Transmembrane Transporter Binding Ceramide Binding
	Biological Process	Microtubule-based Movement Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Cell Division	Behavioral Fear Response Monoatomic Ion Transport Monoatomic Anion Transport Lipid Transport Apoptotic Process Chemical Synaptic Transmission Neuron-neuron Synaptic Transmission Learning Epithelial Cell Differentiation Calcium Import Into The Mitochondrion Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Transmembrane Transport Monoatomic Anion Transmembrane Transport Negative Regulation Of Calcium Import Into The Mitochondrion Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion Positive Regulation Of Type 2 Mitophagy Mitochondrial Transmembrane Transport Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Mitochondrial protein import PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport
Drugs			Aluminium monostearate Cannabidiol Medical Cannabis Nabiximols
Diseases
GWAS			Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: C2orf15 CCL28 CD5 DYNC1I1 DYNC1I2 NIF3L1 PMS1 PVR TESC VDAC1 ZC3H14	26 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DUX4 DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PLAT PPIF PRKCE PRKN RAF1 RNF31 SAMM50 STUB1 SUMO4 TOMM20 TUBA4A
Entrez ID		6990	7416
HPRD ID		02249	05137
Ensembl ID		ENSG00000165169	ENSG00000213585
Uniprot IDs		P51808	A0A1L1UHR1 B3KTS5 P21796
PDB IDs			2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73 6TIQ 6TIR 7QI2 8J0O
Enriched GO Terms of Interacting Partners?		Dynein Light Chain Binding Dynein Heavy Chain Binding Cytoplasmic Dynein Complex	Mitochondrial Outer Membrane Bcl-2 Family Protein Complex Apoptotic Mitochondrial Changes Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Organization Mitochondrial Membrane Organization Mitochondrion Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrion Organization Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Release Of Cytochrome C From Mitochondria Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Membrane Permeability BH3 Domain Binding Regulation Of Mitochondrial Membrane Potential Regulation Of Apoptotic Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Mitochondrial Membrane Permeability Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Membrane Permeability Positive Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Channel Activity Programmed Cell Death Thymocyte Apoptotic Process Cell Death Leukocyte Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Programmed Cell Death Regulation Of Proteolysis Response To Stress Regulation Of IRE1-mediated Unfolded Protein Response BAK Complex B Cell Negative Selection Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Protein-containing Complex Assembly Cellular Response To Unfolded Protein Mitochondrial Fusion Positive Regulation Of Intracellular Signal Transduction Membrane Organization Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Establishment Of Protein Localization To Mitochondrion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?