MYOZ3 and LONRF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYOZ3	LONRF1
Description		myozenin 3	LON peptidase N-terminal domain and ring finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Z Disc	Cytoplasm Cytosol
	Molecular Function	Actin Binding Protein Binding Telethonin Binding FATZ Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)
Interacting Genes		71 interacting genes: ABI2 ACTN1 ACTN2 AKIRIN2 ASPG ATOSB ATXN1L BAG4 BCAS2 C10orf55 CCDC57 CIMIP2B CREM CRLF3 DAZAP2 DMRT3 EFS ENKD1 EXOC8 FAM168B FHL3 FHL5 FLNC GCM2 GOLGA6A GOLGA6L9 HSF2BP KANK2 KRT34 KRT36 KRT75 KRTAP19-5 KRTAP19-6 KRTAP6-1 KRTAP7-1 KRTAP8-1 KYNU LDB3 LENG8 LMO2 LMO3 LMO4 LONRF1 MAPK6 MORN3 MRPL38 MYO15B NEK6 NUTF2 PDLIM3 PITX1 PM20D2 PPP3CA PPP3CB PRDM6 PSMB4 PTK6 RINT1 RNF125 RUSC1 SPMIP5 TBX15 TCAP TEKT4 TRAPPC6A TSC1 TSSK3 UFSP1 YPEL3 ZNF620 ZNF688	98 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DSCR9 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 GPRASP3 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A RSPH1 SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2
Entrez ID		91977	91694
HPRD ID		17624	08674
Ensembl ID		ENSG00000164591	ENSG00000154359
Uniprot IDs		Q8TDC0	Q17RB8
PDB IDs
Enriched GO Terms of Interacting Partners?		Z Disc Intermediate Filament Muscle Cell Development Cytoskeletal Protein Binding Cytoskeleton Organization Protein Binding Titin Z Domain Binding Sarcomere Organization Pseudopodium FATZ Binding Calmodulin-dependent Protein Phosphatase Activity Striated Muscle Cell Development Negative Regulation Of Calcium Ion Import Across Plasma Membrane Calcineurin Complex Organelle Organization Actin Filament Stress Fiber Cell Projection Protein Serine/threonine Phosphatase Complex	Intermediate Filament Protein Binding Zinc Ion Binding Protein Modification By Small Protein Conjugation Protein Ubiquitination Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Keratin Filament Post-translational Protein Modification Positive Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of DNA-templated Transcription Transcription Coactivator Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Protein Kinase C Inhibitor Activity Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Positive Regulation Of Biosynthetic Process Regulation Of Viral Transcription Regulation Of RNA Metabolic Process Protein Modification Process Establishment Of Spindle Localization Structural Constituent Of Skin Epidermis RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spindle Localization Non-canonical Inflammasome Complex Assembly Telencephalon Regionalization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Outer Dense Fiber Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Cytosol Protein K63-linked Ubiquitination Negative Regulation Of Viral Process Positive Regulation Of Macromolecule Metabolic Process Nucleus
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