TTC5 and CAVIN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TTC5	CAVIN1
Description		tetratricopeptide repeat domain 5	caveolae associated protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Cytoplasmic Vesicle	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Membrane Protein-containing Complex Membrane Raft
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Ribosome Binding	RNA Binding Protein Binding RRNA Binding RRNA Primary Transcript Binding Identical Protein Binding
	Biological Process	DNA Repair DNA Damage Response Cellular Response To Starvation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of MRNA Catabolic Process	DNA-templated Transcription Termination Transcription Initiation At RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility
Pathways		Regulation of TP53 Activity through Methylation	RNA Polymerase I Transcription Termination RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282)
Interacting Genes		9 interacting genes: CAMK2A CAMK2B CAMK2D CAMK2G CAVIN1 DDIT4L GOLGA6A HDX JMY	24 interacting genes: CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 INO80B KAT5 MECOM MRPL45 NKX2-1 OGT SOCS3 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC UBE2O YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21
Entrez ID		91875	284119
HPRD ID		15584	04433
Ensembl ID		ENSG00000136319	ENSG00000177469
Uniprot IDs		Q86T04 Q8N0Z6	Q6NZI2
PDB IDs		2XVS 6T59 7QWS 8BPO	9EG6 9EGN 9EIU
Enriched GO Terms of Interacting Partners?		Calcium- And Calmodulin-dependent Protein Kinase Complex Calcium/calmodulin-dependent Protein Kinase Activity Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Endocytic Vesicle Membrane Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Periphery Sarcoplasmic Reticulum Membrane Regulation Of Protein Localization To Membrane Calmodulin Binding Regulation Of Synaptic Plasticity Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Postsynaptic Density Regulation Of Skeletal Muscle Adaptation Neuron Projection Regulation Of Metal Ion Transport Protein Serine Kinase Activity Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Protein Serine/threonine Kinase Activity Regulation Of Monoatomic Ion Transport Modulation Of Chemical Synaptic Transmission Protein Kinase Activity Regulation Of Cellular Localization Kinase Activity Regulation Of Muscle System Process Regulation Of Neuron Migration Regulation Of Cardiac Muscle Cell Apoptotic Process Protein Homodimerization Activity Peptidyl-threonine Autophosphorylation 'de Novo' Actin Filament Nucleation Protein Phosphorylation Regulation Of Protein Localization Phosphorylation Identical Protein Binding Regulation Of Endocannabinoid Signaling Pathway Calcium-dependent Protein Serine/threonine Phosphatase Activity Termination Of RNA Polymerase I Transcription RRNA Primary Transcript Binding Protein Autophosphorylation Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of System Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Relaxation Of Cardiac Muscle Glutamate Receptor Binding	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleolus Regulation Of RNA Metabolic Process DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Circadian Rhythm Positive Regulation Of Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Complex Regulation Of Primary Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Chromatin Organization Positive Regulation Of DNA Repair Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Histone H2AK5 Acetyltransferase Activity Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Chromatin Remodeling Regulation Of Macromolecule Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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