TTC5 and JMY

Number of citations of the paper that reports this interaction (PubMedID 11511361)
0

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TTC5	JMY
Description		tetratricopeptide repeat domain 5	junction mediating and regulatory protein, p53 cofactor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Cytoplasmic Vesicle	Autophagosome Membrane Nucleus Nucleoplasm Cytoplasm Cytoskeleton Endomembrane System Membrane Cell Leading Edge Cytoplasmic Vesicle
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Ribosome Binding	Transcription Coactivator Activity Actin Binding Protein Binding Microtubule Binding Arp2/3 Complex Binding
	Biological Process	DNA Repair DNA Damage Response Cellular Response To Starvation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of MRNA Catabolic Process	DNA Repair Regulation Of Transcription By RNA Polymerase II DNA Damage Response Cellular Response To Starvation Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription 'de Novo' Actin Filament Nucleation Actin Polymerization-dependent Cell Motility Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways		Regulation of TP53 Activity through Methylation	Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282)	Blood and toenail selenium levels ( 25343990) Cryptococcosis in HIV infection ( 33269293) Platelet distribution width ( 32888494) Toenail selenium levels ( 25343990)
Interacting Genes		9 interacting genes: CAMK2A CAMK2B CAMK2D CAMK2G CAVIN1 DDIT4L GOLGA6A HDX JMY	8 interacting genes: CCDC136 EP300 GOLGA6L9 MDM2 MTUS2 RBM48 RINT1 TTC5
Entrez ID		91875	133746
HPRD ID		15584	05045
Ensembl ID		ENSG00000136319	ENSG00000152409
Uniprot IDs		Q86T04 Q8N0Z6	Q8N9B5
PDB IDs		2XVS 6T59 7QWS 8BPO
Enriched GO Terms of Interacting Partners?		Calcium- And Calmodulin-dependent Protein Kinase Complex Calcium/calmodulin-dependent Protein Kinase Activity Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Endocytic Vesicle Membrane Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Periphery Sarcoplasmic Reticulum Membrane Regulation Of Protein Localization To Membrane Calmodulin Binding Regulation Of Synaptic Plasticity Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Postsynaptic Density Regulation Of Skeletal Muscle Adaptation Neuron Projection Regulation Of Metal Ion Transport Protein Serine Kinase Activity Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Protein Serine/threonine Kinase Activity Regulation Of Monoatomic Ion Transport Modulation Of Chemical Synaptic Transmission Protein Kinase Activity Regulation Of Cellular Localization Kinase Activity Regulation Of Muscle System Process Regulation Of Neuron Migration Regulation Of Cardiac Muscle Cell Apoptotic Process Protein Homodimerization Activity Peptidyl-threonine Autophosphorylation 'de Novo' Actin Filament Nucleation Protein Phosphorylation Regulation Of Protein Localization Phosphorylation Identical Protein Binding Regulation Of Endocannabinoid Signaling Pathway Calcium-dependent Protein Serine/threonine Phosphatase Activity Termination Of RNA Polymerase I Transcription RRNA Primary Transcript Binding Protein Autophosphorylation Protein Localization To Extracellular Region Establishment Of Protein Localization To Extracellular Region Protein Secretion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of System Process Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Relaxation Of Cardiac Muscle Glutamate Receptor Binding	Response To Estrogen Positive Regulation Of Establishment Of Protein Localization Peptidyl-lysine Propionylation DNA Damage Response Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Protein Destabilization Histone Butyryltransferase Activity Positive Regulation Of Nucleocytoplasmic Transport Cellular Response To Nutrient Levels Histone Crotonyltransferase Activity Regulation Of Intracellular Transport Positive Regulation Of Protein Transport Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Response To Formaldehyde Cellular Response To Vitamin B1 P53 Binding Histone H2B Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Cellular Response To Light Stimulus Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Cellular Response To UV Histone H3K18 Acetyltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Thigmotaxis Histone H3K27 Acetyltransferase Activity Regulation Of Protein Transport Positive Regulation Of Intracellular Protein Transport Peptide Crotonyltransferase Activity Positive Regulation Of Protein Localization Signal Transduction By P53 Class Mediator Peptide Lactyltransferase (CoA-dependent) Activity Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Response To Vitamin B1 Response To Water-immersion Restraint Stress Cellular Response To Actinomycin D Dsl1/NZR Complex Modulation Of Process Of Another Organism Response To Nutrient Levels
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