SCAF11 and SNRNP70

Number of citations of the paper that reports this interaction (PMID 9447963)
8

Data Source:
HPRD (in vitro, two hybrid)

		SCAF11	SNRNP70
Gene Name		SR-related CTD-associated factor 11	small nuclear ribonucleoprotein 70kDa (U1)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 U2AF2	43 interactors: APP ARSF CDKL3 CEP63 CHERP CLK2 CRP CSNK2A1 CTDP1 DDX17 GEMIN2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2
Entrez ID		9169	6625
HPRD ID		04720	01617
Ensembl ID			ENSG00000104852
Uniprot IDs		Q99590	P08621 Q9UFS1
PDB IDs			2L5I 2L5J 3CW1 3PGW
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing MRNA Metabolic Process Nucleocytoplasmic Transport RNA 3'-end Processing Nuclear Transport RNA Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Gene Expression Cytoplasmic Transport RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Intracellular Transport Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Establishment Of Localization In Cell Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Cellular Localization Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of RNA Splicing Regulation Of Gene Expression Negative Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Metabolic Process Cajal-Retzius Cell Differentiation Beta-amyloid Formation	RNA Processing RNA Metabolic Process Gene Expression MRNA Processing RNA Splicing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Nitrogen Compound Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Cellular Macromolecular Complex Assembly Mesonephros Development Spliceosomal Complex Assembly Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Cellular Metabolic Process Response To Growth Factor Kidney Epithelium Development Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of RNA Splicing Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Component Assembly Primary MiRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Differentiation Regulation Of Metabolic Process Regulation Of Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway BMP Signaling Pathway Embryonic Pattern Specification Anatomical Structure Development Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of MRNA Processing
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