SCAF11 and SRSF2

Number of citations of the paper that reports this interaction (PMID 9447963)
8

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		SCAF11	SRSF2
Gene Name		SR-related CTD-associated factor 11	serine/arginine-rich splicing factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm PML Body Nuclear Speck Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Poly(A) RNA Binding	Nucleotide Binding Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of Nucleic Acid-templated Transcription
Pathways			mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 U2AF2	33 interactors: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRSF1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		9169	6427
HPRD ID		04720	02888
Ensembl ID			ENSG00000161547
Uniprot IDs		Q99590	Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA Processing MRNA 3'-end Processing Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing MRNA Metabolic Process Nucleocytoplasmic Transport RNA 3'-end Processing Nuclear Transport RNA Processing Nuclear Export MRNA Transport RNA Transport RNA Localization Gene Expression Cytoplasmic Transport RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Intracellular Transport Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Establishment Of Localization In Cell Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Cellular Localization Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of RNA Splicing Regulation Of Gene Expression Negative Regulation Of Gene Expression Cellular Metabolic Process Regulation Of Metabolic Process Cajal-Retzius Cell Differentiation Beta-amyloid Formation	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Nuclear Export Spliceosomal Complex Assembly MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA 3'-end Processing Regulation Of MRNA Processing RNA 3'-end Processing MRNA Transport RNA Transport Cellular Macromolecular Complex Assembly RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Cell Cycle Regulation Of RNA Splicing Regulation Of Cell Cycle Cytoplasmic Transport Cellular Metabolic Process Mitotic Cell Cycle Cell Cycle Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Intracellular Transport RNA Biosynthetic Process Mitotic Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Component Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome DNA Strand Elongation Involved In DNA Replication Cellular Localization DNA Strand Elongation Regulation Of Protein Export From Nucleus
Tagcloud ?			asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Difference) ?			asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Intersection) ?