INTS6

Description		integrator complex subunit 6
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Actin Cytoskeleton Integrator Complex INTAC Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II SnRNA 3'-end Processing Protein Localization To Chromatin RNA Polymerase II Transcription Initiation Surveillance
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757)
Interacting Genes		2 interacting genes: CTDP1 MCM7
Entrez ID		26512
HPRD ID		05063
Ensembl ID		ENSG00000102786
Uniprot IDs		B3KU90 Q9UL03
PDB IDs		7BV7 7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?		CMG Complex Double-strand Break Repair Via Break-induced Replication DNA Strand Elongation Involved In DNA Replication Single-stranded DNA Helicase Activity Regulation Of DNA-templated DNA Replication Initiation DNA Strand Elongation MCM Complex Tat Protein Binding TFIIF-class Transcription Factor Complex Binding Host-mediated Activation Of Viral Transcription Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Exit From Mitosis DNA Replication Initiation Negative Regulation Of Cardiac Muscle Tissue Growth Spindle Midzone Host-mediated Perturbation Of Viral Transcription DNA Helicase Activity Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Muscle Hypertrophy Host-mediated Activation Of Viral Process Negative Regulation Of Organ Growth Negative Regulation Of Cardiac Muscle Hypertrophy Cellular Response To Epidermal Growth Factor Stimulus Transcription Elongation By RNA Polymerase II Response To Epidermal Growth Factor DNA-templated Transcription Elongation Hydrolase Activity Cellular Response To Xenobiotic Stimulus Regulation Of Heart Growth Host-mediated Perturbation Of Viral Process Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity Regulation Of Striated Muscle Cell Differentiation Regulation Of Organ Growth Negative Regulation Of Developmental Growth Single-stranded DNA Binding Host-mediated Perturbation Of Symbiont Process Regulation Of DNA Replication Nucleic Acid Metabolic Process Modulation Of Process Of Another Organism Helicase Activity Dephosphorylation Double-strand Break Repair Via Homologous Recombination Phosphoprotein Phosphatase Activity Recombinational Repair DNA Replication
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