PDCD5 and UTP14A

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		PDCD5	UTP14A
Description		programmed cell death 5	UTP14A small subunit processome component
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding	RNA Binding Protein Binding
	Biological Process	Apoptotic Process Positive Regulation Of Gene Expression Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Protein Folding	RRNA Processing Ribosome Biogenesis
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Immature fraction of reticulocytes ( 32888494) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252 32888494) Mean platelet volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet count ( 32888494) Red cell distribution width ( 27863252 32888494) Systemic lupus erythematosus ( 33272962)
Interacting Genes		16 interacting genes: ACP5 CDC42 CEBPA CEP126 EEF1G KAT5 KDM1A LRIF1 NUDT3 OTUD5 PICK1 RAD18 TRIM35 UBE2D3 UTP14A VHL	54 interacting genes: AKTIP APLP1 APP ARIH2 AXIN1 BICD2 CCDC106 CCDC85B CEP70 CPE CSNK2A1 CSNK2B DLEU1 EXOSC8 GADD45G HNRNPH3 HOOK1 HOOK2 HTT KRT31 LAMTOR5 LDOC1 LMO1 LSM3 NIN NINL PDCD5 PDZK1IP1 PHF10 PRKCZ PSG1 PTEN PTPRS RABIF RGS1 RHOH RNF10 RPA2 RSRC1 SAT1 SMYD1 SNRNP48 SSR1 TERF1 TFIP11 TINAGL1 TP53 TP53BP2 TRDMT1 TXLNB USO1 VIM WDR33 ZNF24
Entrez ID		9141	10813
HPRD ID		06843	06712
Ensembl ID		ENSG00000105185	ENSG00000156697
Uniprot IDs		O14737	Q9BVJ6
PDB IDs		1YYB 2CRU 2K6B	7MQ8 7MQ9 7MQA 7WTS
Enriched GO Terms of Interacting Partners?		Protein Modification Process DNA-binding Transcription Factor Binding Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Protein Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Superoxide Anion Generation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Macrophage Differentiation Neuron Projection Organization Ubiquitin Protein Ligase Activity Dendritic Spine Organization Postsynapse Organization RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Gamma-glutamyl Carboxylase Activity Histone H2AK5 Acetyltransferase Activity DNA Repair-dependent Chromatin Remodeling Positive Regulation Of Chromosome Segregation Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Diphosphoinositol Polyphosphate Catabolic Process Rad6-Rad18 Complex Post-translational Protein Modification Cellular Response To Glucose Starvation Negative Regulation Of Macromolecule Metabolic Process GBD Domain Binding Storage Vacuole Transcription Regulator Complex Negative Regulation Of Transcription By RNA Polymerase II Response To Vitamin B2 C/EBP Complex Vitamin Binding Negative Regulation Of Bone Development Protein Monoubiquitination Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity Inositol Phosphate Catabolic Process Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Positive Regulation Of Cell Cycle Process Protein Autoubiquitination Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Cell Cycle CHOP-C/EBP Complex Cellular Response To Stress	FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm Microtubule Cytoskeleton Organization Microtubule Anchoring At Microtubule Organizing Center HOPS Complex MRNA Metabolic Process Identical Protein Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body PML Body Cellular Response To Norepinephrine Stimulus Response To Norepinephrine Cellular Localization Organelle Organization Microtubule Anchoring Early Endosome To Late Endosome Transport P53 Binding Dynein Light Intermediate Chain Binding Apoptotic Process Positive Regulation Of Aggrephagy Central Nervous System Development Cytoplasm Programmed Cell Death Cell Death Positive Regulation Of Excitatory Postsynaptic Potential Fibrillar Center Microtubule-based Process Cytoskeleton Organization Microtubule Organizing Center Intracellular Transport Nucleus Cytoskeleton-dependent Intracellular Transport G-rich Strand Telomeric DNA Binding Cellular Response To Muramyl Dipeptide Modulation Of Excitatory Postsynaptic Potential Developmental Cell Growth Microtubule Anchoring At Centrosome Regulation Of Nervous System Process Endosome To Lysosome Transport Nuclear Matrix Supramolecular Fiber Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Cycle Negative Regulation Of Neurogenesis Centrosome Nucleoplasm Dynactin Binding Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Nervous System Development Cytoplasmic Microtubule Organization
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