PDCD5

Gene Name		programmed cell death 5
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	DNA Binding Protein Binding Heparin Binding Acetyltransferase Activator Activity Beta-tubulin Binding
	Biological Process	Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chaperone-mediated Protein Folding
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640)
Protein-protein Interactions		10 interactors: ACP5 EEF1G KAT5 KDM1A KIAA1377 LRIF1 NUDT3 UBE2D3 UTP14A VHL
Entrez ID		9141
HPRD ID		06843
Ensembl ID		ENSG00000105185
Uniprot IDs		B4DE64 O14737
PDB IDs		1YYB 2CRU 2K6B
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Cytokine Production Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Superoxide Anion Generation Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Oxygen Levels Cellular Nitrogen Compound Metabolic Process Regulation Of Cytokine Production Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nitrogen Compound Metabolic Process Riboflavin Metabolic Process Cellular Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hormone Biosynthetic Process Regulation Of Superoxide Anion Generation Proteasomal Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Nitric Oxide Biosynthetic Process RNA Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Hypoxia Cellular Aromatic Compound Metabolic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Granulocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Megakaryocyte Differentiation
Tagcloud ?		ablation cascade conversely defective diminishes efficiently genotoxic hybrid ineffectiveness interacting knocking linking obscure overcame programmed proteosomal rescued restoration reversed screen strikingly substantially tp53 uncovered yaf2 yy1