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UBE2M and MARCH7
Number of citations of the paper that reports this interaction (PMID
24905733
)
0
Data Source:
BioGRID
(two hybrid)
UBE2M
MARCH7
Gene Name
ubiquitin-conjugating enzyme E2M
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ribosomal S6-glutamic Acid Ligase Activity
NEDD8 Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Zinc Ion Binding
Ligase Activity
Biological Process
Cellular Protein Modification Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Protein Ubiquitination
Positive Regulation Of Neuron Apoptotic Process
Protein Neddylation
Protein Ubiquitination
Pathways
Loss of Function of TGFBR2 in Cancer
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Antigen processing: Ubiquitination & Proteasome degradation
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Class I MHC mediated antigen processing & presentation
SMAD4 MH2 Domain Mutants in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
24 interactors:
APP
CAND1
CBL
CPNE1
CPNE2
CPNE4
CUL1
CUL3
CUL7
DCUN1D3
DCUN1D4
MARCH7
MDM2
NAE1
NEDD4
NEDD8
PARK2
PINK1
RBX1
RNF111
RNF7
TP53
UBA3
UBC
15 interactors:
MAPT
PPP3CA
PPP3CB
RNF111
TRIM65
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2K
UBE2M
UBE2N
USP7
VAV2
Entrez ID
9040
64844
HPRD ID
04414
09817
Ensembl ID
ENSG00000130725
Uniprot IDs
P61081
Q9H992
PDB IDs
1TT5
1Y8X
2NVU
3TDU
3TDZ
4GAO
Enriched GO Terms of Interacting Partners
?
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Protein Neddylation
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Protein Modification Process
Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Cellular Protein Metabolic Process
Protein Monoubiquitination
Proteolysis
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Proteolysis
Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Cellular Response To Hypoxia
Regulation Of Mitochondrion Degradation
Cellular Response To Decreased Oxygen Levels
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Protein Catabolic Process
Regulation Of Cell Cycle Phase Transition
Cellular Response To Oxygen Levels
Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle
Positive Regulation Of Protein Ubiquitination
Catabolic Process
Notch Signaling Pathway
Regulation Of Cell Cycle Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Mitotic Cell Cycle
Negative Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Catabolic Process
Viral Process
Protein Polyubiquitination
Negative Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Protein Metabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Protein Catabolic Process
Apoptotic Process
Cellular Response To Toxic Substance
Regulation Of Proteolysis
Positive Regulation Of Cell Cycle Process
Signaling
Mitotic Cell Cycle Process
Response To Oxidative Stress
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Protein Catabolic Process
Protein K48-linked Ubiquitination
Immune Response-regulating Signaling Pathway
Cellular Macromolecule Catabolic Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Protein Modification Process
Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Regulation Of Immune Response
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Ubiquitination
Activation Of Innate Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Proteolysis
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Innate Immune Response
Cellular Response To Transforming Growth Factor Beta Stimulus
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Response To Transforming Growth Factor Beta
Positive Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination
Cellular Protein Metabolic Process
Positive Regulation Of Ligase Activity
Catabolic Process
Response To Organic Substance
Fc-epsilon Receptor Signaling Pathway
Cellular Response To Organic Substance
Immune Response
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Immune System Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Innate Immune Response
Defense Response
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Fc Receptor Signaling Pathway
Tagcloud
?
acts
affects
balance
brca1
breaks
choice
controller
controlling
ctip
cytotoxic
deneddylation
great
homologous
indeed
neddylation
nhej
recombination
repair
repaired
resection
respond
rnf111
ssdna
strand
subpathways
tight
toward
uncover
way
Tagcloud (Difference)
?
acts
affects
balance
brca1
breaks
choice
controller
controlling
ctip
cytotoxic
deneddylation
great
homologous
indeed
neddylation
nhej
recombination
repair
repaired
resection
respond
rnf111
ssdna
strand
subpathways
tight
toward
uncover
way
Tagcloud (Intersection)
?