UBTF and CD3EAP

Number of citations of the paper that reports this interaction (PMID 9426281)
10

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		UBTF	CD3EAP
Gene Name		upstream binding transcription factor, RNA polymerase I	CD3e molecule, epsilon associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus	RNA Polymerase I Transcription Factor Complex Nucleus Nucleoplasm Chromosome Nucleolus DNA-directed RNA Polymerase I Complex Cytoplasm Mitochondrion
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Poly(A) RNA Binding	DNA-directed RNA Polymerase Activity Poly(A) RNA Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase I Promoter	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway RRNA Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase I Promoter Opening	NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: CCNA2 CCND1 CCNE1 CD3EAP CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2	8 interactors: CD3E NCL NFKBIB POLR1C POLR1D POLR1E TAF1A UBTF
Entrez ID		7343	10849
HPRD ID		02814	00125
Ensembl ID		ENSG00000108312	ENSG00000117877
Uniprot IDs		P17480	O15446
PDB IDs		1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Chromatin Silencing At RDNA Cellular Macromolecule Biosynthetic Process Gene Expression Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle Regulation Of Cell Cycle Phase Transition RNA Metabolic Process Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Chromatin Silencing Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Mitotic Cell Cycle Checkpoint Regulation Of RNA Metabolic Process Cell Division Positive Regulation Of Cellular Biosynthetic Process Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Proliferation Regulation Of Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Gene Expression, Epigenetic Negative Regulation Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cell Cycle Checkpoint Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway RRNA Transcription	Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Elongation Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Initiation Positive Regulation Of Type I Interferon Production Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Type I Interferon Production Positive Regulation Of Cytokine Production Regulation Of Cytokine Production Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Transcription From RNA Polymerase I Promoter Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Innate Immune Response Regulation Of Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Immune System Process Macromolecule Biosynthetic Process Immune Response Defense Response Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of T Cell Anergy Nitrogen Compound Metabolic Process Regulation Of T Cell Anergy Positive Regulation Of T Cell Tolerance Induction Negative Thymic T Cell Selection Signal Complex Assembly Positive Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Interleukin-2 Biosynthetic Process Negative T Cell Selection Chromatin Silencing At RDNA Thymic T Cell Selection
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