UBTF and TAF1B

Number of citations of the paper that reports this interaction (PMID 10913176)
53

Data Source:
BioGRID (pull down)

		UBTF	TAF1B
Gene Name		upstream binding transcription factor, RNA polymerase I	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleus Nucleoplasm Extracellular Vesicular Exosome RNA Polymerase I Core Factor Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Poly(A) RNA Binding	RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding Transcription Factor Recruiting Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding TBP-class Protein Binding Metal Ion Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase I Promoter	Chromatin Silencing At RDNA RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase I Promoter Opening	NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		31 interactors: CCNA2 CCND1 CCNE1 CD3EAP CDK2 CDK4 CENPC CHGB CREBBP CSNK2A1 IRS1 IRS2 LEF1 MAD1L1 MAPK1 MAPK3 MDM2 POLR1E RB1 RBL2 RUNX2 SERPINH1 SMURF1 TAF1 TAF1A TAF1B TAF1C TAF1D TBP TCOF1 ZMYM2	24 interactors: APP EP300 ESR1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TAF1D TBP THAP7 TP53 TRB TRIM24 UBTF
Entrez ID		7343	9014
HPRD ID		02814	05363
Ensembl ID		ENSG00000108312	ENSG00000115750
Uniprot IDs		P17480	Q53T94
PDB IDs		1K99 1L8Y 1L8Z 2HDZ
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Chromatin Silencing At RDNA Cellular Macromolecule Biosynthetic Process Gene Expression Regulation Of Mitotic Cell Cycle Phase Transition Cell Cycle Regulation Of Cell Cycle Phase Transition RNA Metabolic Process Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Chromatin Silencing Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Mitotic Cell Cycle Checkpoint Regulation Of RNA Metabolic Process Cell Division Positive Regulation Of Cellular Biosynthetic Process Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Proliferation Regulation Of Cell Cycle Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Gene Expression, Epigenetic Negative Regulation Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Cell Cycle Checkpoint Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway RRNA Transcription	Negative Regulation Of Gene Expression DNA-templated Transcription, Initiation Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Transcription Initiation From RNA Polymerase I Promoter Negative Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase I Promoter Negative Regulation Of Gene Expression, Epigenetic Gene Expression Chromatin Silencing Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase I Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Silencing Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Termination Positive Regulation Of Transcription, DNA-templated Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Viral Process DNA Packaging Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Biosynthetic Process DNA Conformation Change
Tagcloud ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf
Tagcloud (Difference) ?			analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf
Tagcloud (Intersection) ?