CPNE1 and STK3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CPNE1	STK3
Gene Name		copine I	serine/threonine kinase 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Nucleus Cytoplasm Cytosol
	Molecular Function	Phosphatidylserine Binding Transporter Activity Calcium-dependent Phospholipid Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine/threonine Kinase Activator Activity Protein Dimerization Activity
	Biological Process	Lipid Metabolic Process Vesicle-mediated Transport	Neural Tube Formation Endocardium Development Protein Phosphorylation Apoptotic Process Signal Transduction Central Nervous System Development Negative Regulation Of Cell Proliferation Signal Transduction By Phosphorylation Positive Regulation Of Protein Binding Hippo Signaling Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Positive Regulation Of JNK Cascade Negative Regulation Of Organ Growth Protein Stabilization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Kinase B Signaling Primitive Hemopoiesis Cell Differentiation Involved In Embryonic Placenta Development Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Canonical Wnt Signaling Pathway Hepatocyte Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ACTB BCOR BUB3 CCDC22 CPNE4 LIG4 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 STK3 UBE2M UBE2O WTAP	33 interactors: AKT1 CASP3 CNKSR1 CPNE1 DDAH2 EIF4EBP1 FAM9B GAD1 GBP2 GMCL1 HSPE1 KHSRP LATS1 LATS2 LRRK2 MBP MOB4 MPP1 ORM2 PEX19 PHAX QARS RAF1 RASSF1 RASSF2 RASSF4 RASSF5 SAV1 SLMAP SULT2A1 TFPT TRAF1 ZC3H7A
Entrez ID		8904	6788
HPRD ID		05014	05433
Ensembl ID		ENSG00000214078	ENSG00000104375
Uniprot IDs		B0QZ18 Q99829	B3KYA7 Q13188
PDB IDs			4HKD 4L0N 4LG4 4LGD
Enriched GO Terms of Interacting Partners?		Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Heterooligomerization Regulation Of Cellular Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Organelle Organization In Utero Embryonic Development Protein Monoubiquitination Generation Of Neurons Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Process Actin Filament Capping Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Neurogenesis Negative Regulation Of Histone H3-K36 Methylation DNA Ligation Involved In DNA Recombination Positive Regulation Of Cell Death Anatomical Structure Morphogenesis Negative Regulation Of Actin Filament Depolymerization Regulation Of Intracellular Signal Transduction Mitotic Cell Cycle Process Cellular Protein Metabolic Process Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Mitotic Nuclear Division Cellular Component Assembly Negative Regulation Of Tooth Mineralization Protein Metabolic Process Mitotic Cell Cycle Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Negative Regulation Of Chromosome Organization Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Protein Complex Disassembly Axon Guidance Positive Regulation Of Cell Differentiation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Regulation Of Protein Depolymerization	Hippo Signaling Intracellular Signal Transduction Response To Stimulus Signaling Cell Communication Keratinocyte Differentiation Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Metabolic Process Signal Transduction Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Epidermal Cell Differentiation Cell Death Death Negative Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Death Positive Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Kinase Activity Nitric Oxide Biosynthetic Process Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Organic Substance Skin Development Negative Regulation Of Kinase Activity Programmed Cell Death Posttranscriptional Regulation Of Gene Expression Regulation Of Protein Kinase Activity Mitotic Cell Cycle Phase Transition Regulation Of Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Epidermis Development Cellular Response To Organic Substance Negative Regulation Of Catalytic Activity Regulation Of Kinase Activity Reactive Oxygen Species Metabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Epithelial Cell Differentiation Negative Regulation Of Oxidative Stress-induced Cell Death
Tagcloud ?		affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Difference) ?		affect arrangement cdnas coding connection conservation copine courses ests evolutionary exons genome genomic indicates initiated motif pairs phenomenon promoters rbm12 sequences share sharing shed splicing tags totally utr zebrafish	contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk4 vapsbinding wwc1 wwc2 wwtr1 yap1
Tagcloud (Intersection) ?