CPNE1 and RDX

Number of citations of the paper that reports this interaction (PubMedID 12522145)
0

Data Source:
HPRD (two hybrid, in vitro)

		CPNE1	RDX
Description		copine 1	radixin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Nuclear Membrane Azurophil Granule Membrane Extracellular Exosome	Ruffle Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Microvillus Adherens Junction Focal Adhesion Membrane Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Stereocilium Cell Projection Apical Part Of Cell Cell Tip Extracellular Exosome Cell Periphery Stereocilium Base
	Molecular Function	Phosphatidylserine Binding Endopeptidase Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Identical Protein Binding Metal Ion Binding NF-kappaB Binding	RNA Binding Actin Binding Protein Binding Cytoskeletal Protein Binding Protein Domain Specific Binding Cadherin Binding Cell Adhesion Molecule Binding Protein Kinase A Binding ATPase Binding
	Biological Process	Proteolysis Lipid Metabolic Process Negative Regulation Of Gene Expression Vesicle-mediated Transport Cell Differentiation Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA Binding Positive Regulation Of Neuron Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Calcium Ion Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Neuron Projection Extension	Regulation Of Cell Shape Positive Regulation Of Gene Expression Protein Kinase A Signaling Microvillus Assembly Regulation Of Rap Protein Signal Transduction Cellular Response To Platelet-derived Growth Factor Stimulus Apical Protein Localization Establishment Of Protein Localization Positive Regulation Of Protein Catabolic Process Barbed-end Actin Filament Capping Actin Filament Capping Establishment Of Endothelial Barrier Establishment Of Protein Localization To Plasma Membrane Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Postsynaptic Neurotransmitter Receptor Diffusion Trapping Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Glycerophospholipid biosynthesis Neutrophil degranulation	Recycling pathway of L1 Recycling pathway of L1 Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs		Theophylline	1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Blood protein levels ( 30072576) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cognitive function ( 24684796) Computer vision syndrome ( 33941792) Coronary artery disease ( 32469254) Multiple sclerosis ( 31604244)
Interacting Genes		22 interacting genes: ACTB BCOR BUB3 CCDC22 CEBPA CPNE4 LHX6 LIG4 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SNCA SORBS3 SPTBN1 STK3 UBE2M UBE2O WTAP	23 interacting genes: ABCC2 ARHGDIA C1QTNF9 CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR FTCD GNA13 ICAM2 ITGB2 L1CAM LINC01554 NHERF1 NHERF2 PRPF38A PSME3 RBPMS ROCK1 TSC1 VPS11
Entrez ID		8904	5962
HPRD ID		05014	01534
Ensembl ID		ENSG00000214078	ENSG00000137710
Uniprot IDs		B0QZ18 Q99829	B0YJ88 P35241 Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Norepinephrine Uptake Cellular Response To Metal Ion Response To Metal Ion Transporter Regulator Activity Tau Protein Binding Regulation Of Protein Localization To Cell Periphery Protein-containing Complex Nucleus Regulation Of Organelle Organization Protein-containing Complex Binding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apical Protein Localization Cellular Response To Lithium Ion Magnesium Ion Binding Protein Domain Specific Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Response To Lithium Ion MAPK Cascade Regulation Of Early Endosome To Late Endosome Transport Structural Constituent Of Cytoskeleton Regulation Of Apoptotic Process Cytoskeleton Regulation Of Programmed Cell Death Nucleoplasm Regulation Of Cellular Component Organization Cortical Cytoskeleton Glutamatergic Synapse Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Catabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Receptor Localization To Synapse Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Differentiation Cell Development Regulation Of Signal Transduction Regulation Of Macromolecule Metabolic Process Positive Regulation Of Developmental Process Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Establishment Of Integrated Proviral Latency Central Nervous System Development Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Supramolecular Fiber Organization Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly	Type 2 Metabotropic Glutamate Receptor Binding Membrane Docking Type 3 Metabotropic Glutamate Receptor Binding Membrane To Membrane Docking Response To Calcium Ion Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Cell Shape Leukocyte Cell-cell Adhesion Protein Localization To Membrane Microvillus Organization Positive Regulation Of Early Endosome To Late Endosome Transport Microvillus Assembly Calcium-dependent Phospholipid Binding Plasma Membrane Response To Metal Ion Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Rho Protein Signal Transduction Microvillus Receptor Internalization Uropod Protein Localization To Plasma Membrane Cellular Response To Calcium Ion Regulation Of Intracellular Signal Transduction Establishment Of Epithelial Cell Apical/basal Polarity Protein Localization To Cell Periphery Regulation Of Early Endosome To Late Endosome Transport Focal Adhesion Extracellular Exosome Associative Learning Cell Periphery Regulation Of Cell Morphogenesis G Protein-coupled Dopamine Receptor Signaling Pathway Cell-matrix Adhesion Ruffle Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Negative Regulation Of Intracellular Signal Transduction Cell-cell Adhesion Acid Secretion Microvillus Membrane Gland Morphogenesis Establishment Of Epithelial Cell Polarity Localization Within Membrane Positive Regulation Of Focal Adhesion Assembly Cortical Actin Cytoskeleton Organization Monocarboxylic Acid Transport Regulation Of Vesicle-mediated Transport Protein-membrane Adaptor Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?