LDB1 and CTDSP1

Number of citations of the paper that reports this interaction (PubMedID 14743429)
0

Data Source:
HPRD (in vivo, in vitro)

		LDB1	CTDSP1
Description		LIM domain binding 1	CTD small phosphatase 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex RNA Polymerase II Transcription Regulator Complex Beta-catenin-TCF Complex	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Enzyme Binding LIM Domain Binding Identical Protein Binding Protein Homodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Hydrolase Activity Phosphatase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription By RNA Polymerase II Cell Adhesion Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellum Development Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Focal Adhesion Assembly Head Development	Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of Neurogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs Cardiogenesis Expression and translocation of olfactory receptors
Drugs			Aspartate beryllium trifluoride Citric acid
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)	Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 27863252 32888494)
Interacting Genes		27 interacting genes: ATXN1 CTDSP1 DNMT3L DSCAM ESR1 IRAK3 ISL1 LCOR LHX1 LHX3 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	43 interacting genes: ACTN3 BAG3 CDCA3 CDKN2C CRYBA2 CSF1R CSTF2T FAAP20 FAM110A FANCL FGFR2 GPSM1 GTF2F1 HUNK ITPKB LCK LDB1 LRRC73 LTBP4 MAPKBP1 MBP MORN3 NOXA1 OSTF1 PDZD4 PLEKHM1 POLR2A PTPN11 RAB3IL1 RPRD2 SAXO4 SCNM1 SDCBP SNAI1 STRA8 TEKT4 TRAPPC6A TYRO3 USP29 WWOX YPEL5 ZBTB16 ZSWIM8
Entrez ID		8861	58190
HPRD ID		09144	05615
Ensembl ID		ENSG00000198728	ENSG00000144579
Uniprot IDs		A0A6E1WJ75 Q86U70	Q9GZU7
PDB IDs		2XJY 2XJZ 2YPA 6TYD 7OB5 7OB8 8HIB 8SSU 9F5B	1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Neuron Projection Guidance Axon Guidance Transcription Regulator Complex Spinal Cord Motor Neuron Cell Fate Specification DNA Binding Cell Differentiation In Spinal Cord Transcription Coregulator Binding Spinal Cord Association Neuron Differentiation Neuron Differentiation Positive Regulation Of Anterior Head Development Central Nervous System Neuron Differentiation Motor Neuron Axon Guidance Neuron Projection Development BHLH Transcription Factor Binding Neuron Fate Specification RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Single-stranded DNA Binding Nuclear Estrogen Receptor Binding Metal Ion Binding Mesendoderm Development Negative Regulation Of RNA Metabolic Process Regionalization Sequence-specific DNA Binding Negative Regulation Of Macromolecule Metabolic Process Vagina Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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