LDB1 and CTDSP1

Number of citations of the paper that reports this interaction (PMID 14743429)
3

Data Source:
HPRD (in vitro, in vivo)

		LDB1	CTDSP1
Gene Name		LIM domain binding 1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
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Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Protein Complex	Nucleus Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association	Protein Binding CTD Phosphatase Activity Metal Ion Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of DNA-templated Transcription, Elongation Somatic Stem Cell Maintenance Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hemoglobin Biosynthetic Process	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		26 interactors: ATXN1 CTDSP1 ESR1 IRAK3 ISL1 LHX2 LHX3 LHX6 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	6 interactors: CDCA3 GTF2F1 LDB1 MBP POLR2A SNAI1
Entrez ID		8861	58190
HPRD ID		09144	05615
Ensembl ID		ENSG00000198728	ENSG00000144579
Uniprot IDs		Q86U70	Q9GZU7
PDB IDs		2XJY 2XJZ 2YPA	1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Central Nervous System Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Central Nervous System Development Cellular Metabolic Process Brain Development Head Development Developmental Process Organ Development Anatomical Structure Development Forebrain Development Tube Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Specification Process Cell Differentiation Negative Regulation Of Signal Transduction Multicellular Organismal Development Neuron Differentiation Anatomical Structure Morphogenesis System Development Spinal Cord Motor Neuron Differentiation Generation Of Neurons Negative Regulation Of Signaling Transcription From RNA Polymerase II Promoter Neurogenesis	Negative Regulation Of Cell Differentiation Stem Cell Development 7-methylguanosine MRNA Capping Transcription From RNA Polymerase II Promoter 7-methylguanosine RNA Capping Stem Cell Differentiation Positive Regulation Of Viral Transcription Regulation Of DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Hair Follicle Development Positive Regulation Of Gene Expression Hair Cycle Process Histone H3-K4 Acetylation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Hair Cycle Transcription, RNA-templated Positive Regulation Of Hemoglobin Biosynthetic Process Stem Cell Maintenance Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Defense Response To Nematode Gastrulation Transcription, DNA-templated Negative Regulation Of Vitamin D Biosynthetic Process Regulation Of Hemoglobin Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Nematode Positive Regulation Of Cellular Metabolic Process Epidermis Development Notch Signaling Involved In Heart Development Negative Regulation Of Erythrocyte Differentiation Regulation Of Tight Junction Assembly Positive Regulation Of Transcription, DNA-templated RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Cerebellar Purkinje Cell Differentiation RNA Metabolic Process
Tagcloud ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Difference) ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Intersection) ?