LDB1 and SSBP1

Number of citations of the paper that reports this interaction (PMID 12381786)
24

Data Source:
HPRD (in vitro)

		LDB1	SSBP1
Gene Name		LIM domain binding 1	single-stranded DNA binding protein 1, mitochondrial
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Protein Complex	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association	Chromatin Binding Single-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of DNA-templated Transcription, Elongation Somatic Stem Cell Maintenance Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hemoglobin Biosynthetic Process	DNA Replication Organelle Organization Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis
Pathways			Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS			Anorexia nervosa ( 23568457)
Protein-Protein Interactions		26 interactors: ATXN1 CTDSP1 ESR1 IRAK3 ISL1 LHX2 LHX3 LHX6 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP	6 interactors: CDK1 CKS1B CKS2 LDB1 POLG YWHAQ
Entrez ID		8861	6742
HPRD ID		09144	02703
Ensembl ID		ENSG00000198728	ENSG00000106028
Uniprot IDs		Q86U70	A4D1U3 B7Z268 Q04837
PDB IDs		2XJY 2XJZ 2YPA	1S3O 2DUD 3ULL
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Central Nervous System Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Central Nervous System Development Cellular Metabolic Process Brain Development Head Development Developmental Process Organ Development Anatomical Structure Development Forebrain Development Tube Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Specification Process Cell Differentiation Negative Regulation Of Signal Transduction Multicellular Organismal Development Neuron Differentiation Anatomical Structure Morphogenesis System Development Spinal Cord Motor Neuron Differentiation Generation Of Neurons Negative Regulation Of Signaling Transcription From RNA Polymerase II Promoter Neurogenesis	Cell Division Histone H3-K4 Acetylation Pronuclear Fusion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Protein Kinase Activity G1/S Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Intracellular Transport Cell Cycle Process Regulation Of Protein Phosphorylation Base-excision Repair, Gap-filling Regulation Of Schwann Cell Differentiation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Protein Localization To Kinetochore Negative Regulation Of Erythrocyte Differentiation Aging Protein Localization To Chromosome, Centromeric Region Regulation Of Phosphorylation Positive Regulation Of Protein Import Into Nucleus, Translocation Mitochondrial DNA Replication Cell Cycle Organelle Organization Cerebellar Purkinje Cell Differentiation Histone Modification Regulation Of Phosphorus Metabolic Process Regulation Of Protein Import Into Nucleus, Translocation Cerebellar Purkinje Cell Layer Morphogenesis Mitotic G2 DNA Damage Checkpoint Regulation Of Intracellular Transport Ventricular Cardiac Muscle Cell Development Epithelial Structure Maintenance Mitochondrial DNA Metabolic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Response To Copper Ion Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Tagcloud ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Difference) ?		assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose	agtpbp1 atic calb1 cct4 copa fabp7 h2afy hierarchical ids milieu neurofibrillary omnibus organized prdx3 rnf14 sap18 senile sfpq smarcb1 sorl1 stxbp3 syncrip syne2 tangles tmem59 treeview txnl4a ulk2 visualized
Tagcloud (Intersection) ?