MYO5B and RAB11B

Number of citations of the paper that reports this interaction (PMID 11408590)
102

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		MYO5B	RAB11B
Gene Name		myosin VB	RAB11B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Myosin Complex Cytoplasmic Vesicle Membrane Protein Complex Apical Cortex Recycling Endosome Extracellular Vesicular Exosome	Mitochondrion Synaptic Vesicle Cell Junction Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Phagocytic Vesicle Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Renal Water Homeostasis Water Transport Metabolic Process Protein Transport Vesicle-mediated Transport Endosome Localization Transmembrane Transport	Receptor Recycling Intracellular Protein Transport Melanosome Transport Rab Protein Signal Transduction Transferrin Transport Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Anion Transport Constitutive Secretory Pathway Regulated Secretory Pathway Cellular Response To Acidic PH Establishment Of Protein Localization To Membrane Retrograde Transport, Endosome To Plasma Membrane Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AMOTL2 BNIP2 COIL CXCR2 KIAA1549 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 RAB8A SMAD3 TCF4 TRIM54	9 interactors: APP IKBKG MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SREBF2
Entrez ID		4645	9230
HPRD ID		07582	05009
Ensembl ID		ENSG00000167306	ENSG00000185236
Uniprot IDs		Q7Z7A5 Q9H6Y6 Q9ULV0	Q15907
PDB IDs			2F9L 2F9M
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Vesicle Localization Exocytosis Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Organelle Localization Insulin Secretion Involved In Cellular Response To Glucose Stimulus Establishment Of Vesicle Localization Secretion By Cell Cellular Pigmentation Ras Protein Signal Transduction Secretion Positive Regulation Of Cell Migration Establishment Of Organelle Localization Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Signaling Pigmentation Regulation Of Protein Localization Regulation Of Vesicle-mediated Transport Cell Communication Protein Transport Protein Secretion Vesicle-mediated Transport Response To Glucose Establishment Of Protein Localization Chemical Homeostasis Intracellular Protein Transport Positive Regulation Of Cell Morphogenesis Involved In Differentiation Response To Stimulus Positive Regulation Of Cell Development Renal Water Homeostasis Response To Carbohydrate Cellular Response To Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Epithelial To Mesenchymal Transition Glucose Homeostasis Signal Transduction Intracellular Signal Transduction Regulation Of Cell Migration DNA-templated Transcription, Initiation Protein Localization Small GTPase Mediated Signal Transduction Regulation Of Protein Transport Regulation Of Cell Motility Insulin Secretion Water Transport	Cellular Localization Vesicle-mediated Transport Regulated Secretory Pathway Establishment Of Localization In Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Exocytosis Secretion By Cell Renal Water Homeostasis Secretion Homeostatic Process Protein Transport Establishment Of Protein Localization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Insulin Secretion Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Chemical Homeostasis Cellular Response To Glucose Stimulus Water Homeostasis Peptide Hormone Secretion Peptide Secretion Protein Localization Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Transport Hormone Secretion Hormone Transport Peptide Transport Renal System Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Cholesterol Metabolic Process Cellular Chemical Homeostasis Protein Secretion Sterol Metabolic Process Amide Transport Regulation Of Body Fluid Levels Response To Glucose Collateral Sprouting In Absence Of Injury Negative Regulation Of Receptor Recycling Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cholesterol Efflux Cellular Homeostasis Response To Carbohydrate Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Receptor Signaling Pathway Axon Choice Point Recognition Golgi Ribbon Formation
Tagcloud ?		alleles comprising disequilibrium dyslexia english enrichment explores german germany hereditary language linkage loci minor nedd4l nominal reading relevance replicated rs12606138 rs555879 rs8094327 scerri sets snp snps speaking spelling substantiate	app biology causal complemented complexity deposition endosomal exome gtpase gtpases late link membrane network players rab3 recycling retromer retromers rnai road screen secretase secretases trafficking unravel
Tagcloud (Difference) ?		alleles comprising disequilibrium dyslexia english enrichment explores german germany hereditary language linkage loci minor nedd4l nominal reading relevance replicated rs12606138 rs555879 rs8094327 scerri sets snp snps speaking spelling substantiate	app biology causal complemented complexity deposition endosomal exome gtpase gtpases late link membrane network players rab3 recycling retromer retromers rnai road screen secretase secretases trafficking unravel
Tagcloud (Intersection) ?