CDS2 and IL10RA

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		CDS2	IL10RA
Name		CDP-diacylglycerol synthase 2	interleukin 10 receptor subunit alpha
Structure		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane
	Molecular Function	Phosphatidate Cytidylyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Lipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Lipid Droplet Formation	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway
Pathways		Synthesis of PG	Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
GWAS		No GWAS studies recorded	Obesity-related traits ( 23251661 )
Novel Interactors		None recorded	2 novel interactors: DRD2 KMT2A
Interacting Genes		28 interacting genes: BIK CPLX4 CREB3 ERGIC3 FAM209A FKBP7 GPR152 GPX8 HIBADH IL10RA JSRP1 LEUTX LHFPL5 LMNA MR1 MTIF3 MYG1 RNF122 SAR1A SSMEM1 TIMMDC1 TMEM139 TMEM45B TMX2 TRIM55 TRIM63 TSG101 TSPAN12	20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		8760	3587
HPRD ID		09150	00911
Ensembl ID		ENSG00000101290	ENSG00000110324
Uniprot IDs		O95674	Q13651
PDB IDs		Not available	1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
GO Terms Enriched among Interactors		None	Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway