CDS2 and RNF122

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDS2	RNF122
Description		CDP-diacylglycerol synthase 2	ring finger protein 122
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Membrane
	Molecular Function	Phosphatidate Cytidylyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Lipid Droplet Formation	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways		Synthesis of PG
Drugs
Diseases
GWAS			Pulse pressure ( 30578418)
Interacting Genes		28 interacting genes: BIK CPLX4 CREB3 ERGIC3 FAM209A FKBP7 GPR152 GPX8 HIBADH IL10RA JSRP1 LEUTX LHFPL5 LMNA MR1 MTIF3 MYG1 RNF122 SAR1A SSMEM1 TIMMDC1 TMEM139 TMEM45B TMX2 TRIM55 TRIM63 TSG101 TSPAN12	12 interacting genes: AQP1 CDS2 CTSA GPR37L1 PLLP RIGI UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2L6 UBE2N
Entrez ID		8760	79845
HPRD ID		09150	11498
Ensembl ID		ENSG00000101290	ENSG00000133874
Uniprot IDs		O95674	Q9H9V4
PDB IDs
Enriched GO Terms of Interacting Partners?			Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Polyubiquitination Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation ISG15 Transferase Activity Proteolysis Protein Monoubiquitination ISG15-protein Conjugation Post-translational Protein Modification Macromolecule Catabolic Process Transferase Activity Positive Regulation Of Protein Polyubiquitination ATP Binding Regulation Of Protein Polyubiquitination Protein Modification Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Nucleotide Binding TORC1 Signaling Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Catabolic Process Protein Autoubiquitination Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Lumenal Side Of Lysosomal Membrane Antiviral Innate Immune Response Phosphatidate Cytidylyltransferase Activity Prosaposin Receptor Activity Regulation Of Transcytosis Protein Metabolic Process TOR Signaling Ubiquitin Protein Ligase Activity Negative Regulation Of TOR Signaling Positive Regulation Of Saliva Secretion Cellular Response To Mercury Ion Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of TORC1 Signaling UBC13-MMS2 Complex Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
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