ATP5PO and NME6

Number of citations: 72 (PubMedID 27107012)
Data Source: BioGRID (two hybrid)

		ATP5PO	NME6
Name		ATP synthase peripheral stalk subunit OSCP	NME/NM23 nucleoside diphosphate kinase 6
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Cell Surface Membrane Proton-transporting ATP Synthase Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Protein Binding ATP Hydrolysis Activity Protein-containing Complex Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Estradiol Binding	Nucleotide Binding Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Cellular Response To CAMP Cellular Response To Cytokine Stimulus Proton Transmembrane Transport	GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Apoptotic Process Nucleotide Metabolic Process Pyrimidine Ribonucleotide Salvage Negative Regulation Of Cell Growth Negative Regulation Of Mitotic Nuclear Division
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	None
Drugs		Artenimol	None
GWAS		No GWAS studies recorded	Brain morphology (min-P) ( 32665545 ) Brain morphology (MOSTest) ( 32665545 ) Cortical surface area (MOSTest) ( 32665545 ) Subcortical volume (min-P) ( 32665545 ) Subcortical volume (MOSTest) ( 32665545 )
Interacting Genes		19 interacting genes: APP CCDC136 CEP70 ERCC6 GOLGA2 HMBOX1 KRT13 KRT15 MIPOL1 NDC80 NME6 NT5C2 PNMA1 TEX13A TFIP11 TRIP6 USHBP1 ZBTB14 ZNF76	3 interacting genes: APP ATP5PO ZNRD2
Entrez ID		539	10201
HPRD ID		02899	09219
Ensembl ID		ENSG00000241837	ENSG00000172113
Uniprot IDs		P48047	A0A0C4DG91 A0A2R8Y7V2 C9JQB1 O75414
PDB IDs		8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To CAMP Acetylcholine Receptor Activator Activity PTB Domain Binding Response To Purine-containing Compound Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Estradiol Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel