ATP5PO and CBR3

Data Source: HiPPIP (Novel)

		ATP5PO	CBR3
Name		ATP synthase peripheral stalk subunit OSCP	carbonyl reductase 3
Structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Cell Surface Membrane Proton-transporting ATP Synthase Complex	Extracellular Space Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding ATP Hydrolysis Activity Protein-containing Complex Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Estradiol Binding	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor NADPH Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Cellular Response To CAMP Cellular Response To Cytokine Stimulus Proton Transmembrane Transport	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Phase I - Functionalization of compounds
Drugs		Artenimol	None
GWAS		No GWAS studies recorded	Blood protein levels ( 30072576 ) Lumbar spine bone mineral density ( 22504420 )
Novel Interactors		2 novel interactors: CBR3 RCAN1	10 novel interactors: ANK1 ATP5PO CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RCAN1 SHOX2
Interacting Genes		19 interacting genes: APP CCDC136 CEP70 ERCC6 GOLGA2 HMBOX1 KRT13 KRT15 MIPOL1 NDC80 NME6 NT5C2 PNMA1 TEX13A TFIP11 TRIP6 USHBP1 ZBTB14 ZNF76	7 interacting genes: ARIH2 BICD2 RAB35 RANBP9 S100A10 SDCBP UBC
Entrez ID		539	874
HPRD ID		02899	07222
Ensembl ID		ENSG00000241837	ENSG00000159231
Uniprot IDs		P48047	O75828 V9HW40
PDB IDs		8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3	2HRB
GO Terms Enriched among Interactors		Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Cytoskeletal Anchor Activity Plasma Membrane Apical Dendrite