ADAM19 and COPB1

Number of citations of the paper that reports this interaction (PMID 12463424)
1

Data Source:
HPRD (two hybrid)

		ADAM19	COPB1
Gene Name		ADAM metallopeptidase domain 19	coatomer protein complex, subunit beta 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi-associated Vesicle Cytosol Plasma Membrane Membrane COPI Vesicle Coat Intracellular Membrane-bounded Organelle
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding SH3 Domain Binding	Structural Molecule Activity Protein Binding
	Biological Process	Membrane Protein Ectodomain Proteolysis Heart Development	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Viral Process COPI Coating Of Golgi Vesicle Membrane Organization
Pathways			COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS		Pulmonary function ( 20010835) Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		7 interactors: A2M ABI2 COPB1 FURIN NRG1 SH3GL2 TNFSF11	32 interactors: ADAM19 APP ARCN1 ARF1 COPE COPG1 COPG2 ERBB2IP FOXB1 GRB2 HLA-DPB1 HLA-G ID1 IRAK3 KCNK3 KDELR1 LZTS2 NUB1 PDGFRB PRKCE RGS2 RGS4 RHOQ SERTAD1 SNTA1 TANK TAPBP TMED10 TRIM37 UBQLN4 VPS18 XRCC6
Entrez ID		8728	1315
HPRD ID		04704	02981
Ensembl ID		ENSG00000135074	ENSG00000129083
Uniprot IDs		E9PD32 Q8TBU7 Q9H013	P53618
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Acute Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Locomotion Positive Regulation Of Corticotropin-releasing Hormone Secretion Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Extracellular Matrix Disassembly Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Catabolic Process Response To Growth Factor Regulation Of Protein Kinase B Signaling Nerve Growth Factor Production Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling TNFSF11-mediated Signaling Pathway Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Signaling Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Cell Proliferation Epidermal Growth Factor Receptor Signaling Pathway Cell Differentiation ERBB Signaling Pathway Signaling Mammary Gland Development Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Osteoclast Development Nerve Growth Factor Processing Cell Communication Regulation Of Cellular Protein Metabolic Process Cell Migration Osteoclast Proliferation Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Protein Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Production Enzyme Linked Receptor Protein Signaling Pathway Cell Motility MAPK Cascade Regulation Of Protein Metabolic Process Regulation Of Osteoclast Development	Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Intracellular Transport Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Innate Immune Response Cellular Localization Immune Response-regulating Signaling Pathway Regulation Of Cytoskeleton Organization Immune Response Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Immune System Process Regulation Of MAPK Cascade Regulation Of Actin Filament-based Process Regulation Of Organelle Organization Regulation Of Phosphorylation Defense Response Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Organelle Localization ERBB Signaling Pathway Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Regulation Of Actin Cytoskeleton Organization Regulation Of Immune Response Protein Localization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Protein Transport Positive Regulation Of Immune Response Negative Regulation Of MAP Kinase Activity Transport Organelle Localization Regulation Of Phospholipase Activity Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Antigen Cellular Copper Ion Homeostasis Cellular Protein Localization Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation
Tagcloud ?		aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2	ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp
Tagcloud (Difference) ?		aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2	ca037 ca530 cadd chlamydiaceae chlamydophila copd1 copd2 inca incc pkn5 psittaci scc1 scc2 scc3 sctc sctd sctj sctl sctn sctq sctr scts sctt sctu sctv sctw t3s t3ss tarp
Tagcloud (Intersection) ?