ADAM19

Gene Name		ADAM metallopeptidase domain 19
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding SH3 Domain Binding
	Biological Process	Membrane Protein Ectodomain Proteolysis Heart Development
Pathways
Drugs
Diseases
GWAS		Pulmonary function ( 20010835) Pulmonary function (interaction) ( 23284291)
Protein-protein Interactions		7 interactors: A2M ABI2 COPB1 FURIN NRG1 SH3GL2 TNFSF11
Entrez ID		8728
HPRD ID		04704
Ensembl ID		ENSG00000135074
Uniprot IDs		E9PD32 Q8TBU7 Q9H013
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Acute Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Locomotion Positive Regulation Of Corticotropin-releasing Hormone Secretion Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Extracellular Matrix Disassembly Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Catabolic Process Response To Growth Factor Regulation Of Protein Kinase B Signaling Nerve Growth Factor Production Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of ERK1 And ERK2 Cascade Via TNFSF11-mediated Signaling TNFSF11-mediated Signaling Pathway Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Negative Regulation Of Complement Activation, Lectin Pathway Regulation Of Signaling Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Cell Proliferation Epidermal Growth Factor Receptor Signaling Pathway Cell Differentiation ERBB Signaling Pathway Signaling Mammary Gland Development Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Osteoclast Development Nerve Growth Factor Processing Cell Communication Regulation Of Cellular Protein Metabolic Process Cell Migration Osteoclast Proliferation Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Localization Negative Regulation Of Protein Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Production Enzyme Linked Receptor Protein Signaling Pathway Cell Motility MAPK Cascade Regulation Of Protein Metabolic Process Regulation Of Osteoclast Development
Tagcloud ?		aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c nrbf2 parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2