URI1 and DMAP1

Number of citations of the paper that reports this interaction (PMID 15367675)
13

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		URI1	DMAP1
Gene Name		URI1, prefoldin-like chaperone	DNA methyltransferase 1 associated protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus DNA-directed RNA Polymerase II, Core Complex Cytoplasm Mitochondrion Dendrite	Nucleus Nucleoplasm Replication Fork Cytoplasm NuA4 Histone Acetyltransferase Complex
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Chromatin Binding Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Inhibitor Activity	RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Corepressor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Growth Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Response To Virus Negative Regulation Of Phosphatase Activity Cellular Response To Growth Factor Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Repair DNA Methylation Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Growth Positive Regulation Of Transcription Factor Import Into Nucleus Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP ATF7 DMAP1 GTF2F2 ITCH NEDD4 POLR2E RPS6KB1 STAP1	10 interactors: DAXX DNMT1 HDAC2 ING1 MNAT1 MRGBP RGS6 TOMM34 TSG101 URI1
Entrez ID		8725	55929
HPRD ID		11943	05465
Ensembl ID		ENSG00000105176	ENSG00000178028
Uniprot IDs		O94763	B4DQG8 Q9NPF5
PDB IDs			3HM5 4IEJ
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Gene Expression Intracellular Receptor Signaling Pathway Regulation Of Growth 7-methylguanosine MRNA Capping Protein K63-linked Ubiquitination 7-methylguanosine RNA Capping Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Viral Transcription Neuromuscular Junction Development Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Nitrogen Compound Metabolic Process MRNA Processing DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Regulation Of Synapse Structure Or Activity Regulation Of Metabolic Process Interaction With Host Regulation Of Type I Interferon Production Positive Regulation Of Protein Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Skeletal Muscle Tissue Growth Locomotion Positive Regulation Of Mitotic Cell Cycle MRNA Metabolic Process Immune Response Negative Regulation Of Gene Expression RNA Processing Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Collateral Sprouting In Absence Of Injury Notch Signaling Pathway Regulation Of Viral Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Regulation Of Signal Transduction Protein Polyubiquitination Skeletal Muscle Atrophy	Chromatin Modification Regulation Of Growth Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Chromatin Organization Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Organelle Organization Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Cell Proliferation Regulation Of Cell Death Regulation Of Metabolic Process Regulation Of Cell Growth Regulation Of Cellular Component Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Metabolic Process Gene Silencing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Maintenance Of Chromatin Silencing Viral Process Epidermal Cell Differentiation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cell Cycle C-5 Methylation Of Cytosine Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Maintenance Of DNA Methylation Negative Regulation Of MHC Class II Biosynthetic Process Chromatin Remodeling Positive Regulation Of Gene Expression Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?			1p 1p34 ataxia atm avian cip1 coded dnmt1 doxo doxorubicin heterozygosity histology intriguingly loh mycn myelocytomatosis nb nbs neuroblastoma originates paediatric reagent situations stabilisation sympathetic telangiectasia tumourigenesis unfavourable waf1
Tagcloud (Difference) ?			1p 1p34 ataxia atm avian cip1 coded dnmt1 doxo doxorubicin heterozygosity histology intriguingly loh mycn myelocytomatosis nb nbs neuroblastoma originates paediatric reagent situations stabilisation sympathetic telangiectasia tumourigenesis unfavourable waf1
Tagcloud (Intersection) ?