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KRT8
Description
keratin 8
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intermediate Filament
Cell-cell Junction
Apicolateral Plasma Membrane
Nuclear Matrix
Z Disc
Sarcolemma
Keratin Filament
Intermediate Filament Cytoskeleton
Extracellular Exosome
Cell Periphery
Molecular Function
Protein Binding
Scaffold Protein Binding
Biological Process
Tumor Necrosis Factor-mediated Signaling Pathway
Response To Other Organism
Cell Differentiation Involved In Embryonic Placenta Development
Extrinsic Apoptotic Signaling Pathway
Hepatocyte Apoptotic Process
Pathways
Keratinization
Formation of the cornified envelope
Developmental Lineage of Mammary Gland Luminal Epithelial Cells
Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Tenecteplase
Lanoteplase
Copper
Diseases
GWAS
Alanine aminotransferase levels (
33339817
33547301
34315874
)
Aspartate aminotransferase levels (
33547301
34315874
)
Cancer (pleiotropy) (
27197191
)
Gamma glutamyl transferase levels (
29403010
)
Mean reticulocyte volume (
32888494
)
Opioid dependence (time to event) (
34124712
)
Prostate cancer (
21743057
)
Sick sinus syndrome (
33580673
)
Novel Interacting Genes
1 novel interacting genes:
ELOC
Interacting Genes
53 interacting genes:
ANXA1
BYSL
CEP57
CLK1
DEDD
DMD
EGFR
ESR1
FBXO25
FGFR3
GRB2
HSPA5
IKBKG
KIFC3
KPNA2
KRT13
KRT15
KRT16
KRT18
KRT24
KRT25
KRT26
KRT27
KRT28
KRT31
KRT32
KRT33B
KRT35
KRT36
KRT37
KRT38
KRT40
LINC01554
MAPK1
MAPK14
MAPK3
MAPK8
NEK6
OGT
PIWIL2
PKD1
PKP1
PLAT
PNN
PPL
QRSL1
RAF1
SUMO2
TCHP
TFIP11
TRIM54
TROAP
WBP2
Entrez ID
3856
HPRD ID
01015
Ensembl ID
ENSG00000170421
Uniprot IDs
P05787
Q7L4M3
PDB IDs
7K3C
7K3X
7K3Y
Enriched GO Terms of Interacting Partners
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Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Structural Constituent Of Skin Epidermis
Keratin Filament
Intermediate Filament Organization
Intermediate Filament
Structural Molecule Activity
Morphogenesis Of An Epithelium
Tissue Morphogenesis
Epithelial Cell Differentiation
Cytoskeleton Organization
Cytoskeleton
Supramolecular Fiber Organization
Anatomical Structure Morphogenesis
Cellular Developmental Process
Cell Differentiation
Organelle Organization
Developmental Process
Cytosol
Extracellular Exosome
MAP Kinase Activity
Schwann Cell Development
Stress-activated MAPK Cascade
ERBB2 Signaling Pathway
Stress-activated Protein Kinase Signaling Cascade
Desmosome
ERBB3 Signaling Pathway
ERBB2-ERBB3 Signaling Pathway
Response To Mechanical Stimulus
Insulin-like Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
MAPK Cascade
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Hair Cycle
Regulation Of Protein Metabolic Process
Intracellular Signaling Cassette
Tissue Development
Structural Constituent Of Cytoskeleton
Pseudopodium
Protein Kinase Activity
Interleukin-34-mediated Signaling Pathway
Cornified Envelope
Protein Binding
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cyclase Activity
Face Development
Epidermal Growth Factor Receptor Signaling Pathway
Glial Cell Development
Regulation Of Golgi Inheritance
Response To Muscle Stretch
Tagcloud
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