EIF3F and MYOZ1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EIF3F	MYOZ1
Description		eukaryotic translation initiation factor 3 subunit F	myozenin 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Nucleus Actin Cytoskeleton Z Disc Pseudopodium Cell Projection
	Molecular Function	Translation Initiation Factor Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Metallopeptidase Activity Hydrolase Activity Translation Initiation Factor Binding Identical Protein Binding Deubiquitinase Activity Metal-dependent Deubiquitinase Activity	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding Actinin Binding FATZ Binding Molecular Condensate Scaffold Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Proteolysis IRES-dependent Viral Translational Initiation	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Wound Healing Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs		Quercetin
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Depression (quantitative trait) ( 20800221) Malaria ( 31844061) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Atrial fibrillation ( 30061737) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		47 interacting genes: AGR2 APP ATXN1 BTG3 C1orf216 CCDC120 CCDC196 CDC42 CDK11B CDK19 CDSN COL1A2 DKC1 EEF1A1 EIF3M EML2 ERCC6 FBXO32 HAX1 HGS HNRNPK HTR2A KLHL20 LCOR MCPH1 MKRN2 MSH4 MTOR MYDGF MYOZ1 NUP54 OGT PBX4 PKN1 POGZ POU6F2 PTN RABIF RIN1 RPS6KB1 RTP5 SHBG SMAD9 SUOX TEX56P TIMM10B WASHC1	42 interacting genes: ACTN1 ACTN2 ACTN3 ACTN4 AKAP8L APP BAG4 BRCA1 CEACAM6 CEP76 CRX EIF3F EXOSC8 FBXL21P FLNA FLNC GOLGA6A GRB2 GSK3B KRT34 KRT36 KRTAP12-2 LDB3 LHX4 LZTS2 MAGEA11 PFDN5 PLEKHG4 PNKP PNMA1 PRKAA2 TCAP TRAF1 TRIM23 TRIM55 TRIM63 USHBP1 VAC14 VBP1 WASHC3 WWOX YPEL3
Entrez ID		8665	58529
HPRD ID		04887	05725
Ensembl ID		ENSG00000175390	ENSG00000177791
Uniprot IDs		O00303	Q9NP98
PDB IDs		3J8B 3J8C 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN	7A8T 7A8U 7ANK
Enriched GO Terms of Interacting Partners?		Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Glycolytic Process Negative Regulation Of TORC2 Signaling Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of ATP Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Nutrient Positive Regulation Of Nucleobase-containing Compound Metabolic Process Intracellular Protein Localization Positive Regulation Of Translational Initiation Memory Positive Regulation Of RNA Biosynthetic Process Intracellular Signaling Cassette Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Pseudopodium Assembly Skin Morphogenesis Regulation Of TORC2 Signaling Regulation Of Supramolecular Fiber Organization TORC2 Signaling Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Gliogenesis Positive Regulation Of TORC1 Signaling TORC1 Signaling Organelle Organization Positive Regulation Of Macromolecule Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Primary Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Learning Protein Trimerization Positive Regulation Of Transcription By RNA Polymerase III Protein Tyrosine Kinase Activator Activity Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process ATP-dependent DNA Damage Sensor Activity Regulation Of Insulin Receptor Signaling Pathway Regulation Of Gene Expression Response To Auditory Stimulus Mitochondrial Intermembrane Space	Z Disc Pseudopodium Muscle Cell Development Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Apoptotic Process Transmembrane Transporter Binding Regulation Of Programmed Cell Death Identical Protein Binding Cytoskeleton Organization Sarcomere Organization Titin Binding Regulation Of Supramolecular Fiber Organization Titin Z Domain Binding Actin Filament Binding Regulation Of Glycolytic Process Cortical Actin Cytoskeleton Sarcomere Regulation Of Amyloid Fibril Formation Regulation Of Generation Of Precursor Metabolites And Energy Platelet Alpha Granule Lumen Regulation Of Carbohydrate Catabolic Process Cytoskeletal Protein Binding Integrin Binding Actin Binding Regulation Of ATP Metabolic Process Regulation Of Cytoskeleton Organization Focal Adhesion Assembly Cytosol Cytoplasm Actin Filament Positive Regulation Of Supramolecular Fiber Organization FATZ Binding Skeletal Muscle Atrophy Regulation Of Purine Nucleotide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cell-substrate Junction Assembly Skeletal Muscle Adaptation Striated Muscle Atrophy Prefoldin Complex Cell-substrate Junction Organization Anatomical Structure Morphogenesis Structural Constituent Of Muscle Actomyosin Structure Organization Supramolecular Fiber Organization Organelle Organization Muscle Atrophy Positive Regulation Of Organelle Organization Cell Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?