SSNA1 and TXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSNA1	TXN2
Description		SS nuclear autoantigen 1	thioredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Axon Midbody Motile Cilium Ciliary Basal Body Cell Projection Supramolecular Fiber	Nucleolus Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding	Protein Binding Protein-disulfide Reductase Activity
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Nucleation Nervous System Development Axonogenesis Intraciliary Transport Receptor Clustering Axon Extension Cell Division Axon Arborization	Cell Redox Homeostasis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: CDC37 EHHADH FXR1 LNX1 NTAQ1 PICK1 PSMC5 RNF4 SDCBP SPAST TBC1D7 TCEANC TXN2	78 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32
Entrez ID		8636	25828
HPRD ID		10251	07161
Ensembl ID		ENSG00000176101	ENSG00000100348
Uniprot IDs		O43805	Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?			Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process
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