SSNA1 and TXN2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SSNA1	TXN2
Gene Name		Sjogren syndrome nuclear autoantigen 1	thioredoxin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Ciliary Basal Body	Nucleolus Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body
	Molecular Function	Identical Protein Binding	Peptide-methionine (S)-S-oxide Reductase Activity Protein Disulfide Oxidoreductase Activity Protein Complex Binding Peptide-methionine (R)-S-oxide Reductase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Intraciliary Transport Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway	Response To Reactive Oxygen Species Response To Hypoxia Glycerol Ether Metabolic Process Response To Nutrient Response To Hormone Response To Glucose Response To Organic Cyclic Compound Cellular Response To Nutrient Levels Response To Drug Cell Redox Homeostasis Response To Axon Injury Oxidation-reduction Process
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EHHADH GOPC LNX1 SDCBP SPAST TBC1D7 TCEANC TXN2	34 interactors: AGTRAP ALDOB AP2B1 CCDC114 DCTD FAM9B GPRASP2 KRT18 KRT40 MAGEA11 MAPRE2 MAPRE3 MLH1 MRFAP1L1 MTUS2 PPCDC PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SCYL3 SHARPIN SSNA1 STUB1 THAP1 TIFA TRIM21 TRIP6 UCHL5 VIM VPS52 ZBTB14
Entrez ID		8636	25828
HPRD ID		10251	07161
Ensembl ID		ENSG00000176101	ENSG00000100348
Uniprot IDs		O43805	B4DX69 Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Protein Homooligomerization Protein Oligomerization Cytoplasmic Sequestering Of CFTR Protein ER To Golgi Vesicle-mediated Transport Cytokinesis, Completion Of Separation Negative Regulation Of Cilium Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Microtubule Depolymerization Regulation Of Extracellular Vesicular Exosome Assembly Cellular Component Assembly Negative Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Component Organization Mitotic Cytokinetic Process Regulation Of Organelle Organization Protein Hexamerization Regulation Of Golgi To Plasma Membrane Protein Transport Golgi Vesicle Transport Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Complex Assembly Substrate-dependent Cell Migration, Cell Extension Microtubule Severing Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane	Protein Polyubiquitination Cell Cycle Protein Ubiquitination Protein Modification By Small Protein Conjugation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Autoubiquitination Negative Regulation Of Kit Signaling Pathway Meiotic Metaphase I Plate Congression Golgi To Plasma Membrane CFTR Protein Transport Meiotic Spindle Midzone Assembly Regulation Of Proteasomal Protein Catabolic Process I-kappaB Kinase/NF-kappaB Signaling Signal Transduction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Chaperone-mediated Protein Complex Assembly Negative Regulation Of Mitotic Recombination Positive Regulation Of Microtubule Plus-end Binding Fructose Catabolic Process Embryonic Ectodermal Digestive Tract Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Execution Phase Of Apoptosis Nucleotide Metabolic Process Positive Regulation Of Ligase Activity Negative Regulation Of Protein Deubiquitination Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Positive Regulation Of Cell Cycle Apoptotic Process Signaling Nicotinamide Nucleotide Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Mitotic Recombination Pentose-phosphate Shunt, Non-oxidative Branch Fructose 1,6-bisphosphate Metabolic Process Male Meiosis Chromosome Segregation Positive Regulation Of Viral Entry Into Host Cell Programmed Cell Death Cell Communication Protein Complex Assembly Cell Cycle Process Regulation Of Cytokine-mediated Signaling Pathway Cell Death Nucleobase-containing Small Molecule Metabolic Process Death Negative Regulation Of Interleukin-6 Secretion Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Tagcloud ?		auto autoantigen axon axonopathy branching cardinal centrioles centrosomes corticospinal cytokinesis extremity hsp hsps localizing na14 outgrowth paraplegias postulate severing severs sjogren spastic spasticity spastin spatially spg1 spg4 temporally tubulation
Tagcloud (Difference) ?		auto autoantigen axon axonopathy branching cardinal centrioles centrosomes corticospinal cytokinesis extremity hsp hsps localizing na14 outgrowth paraplegias postulate severing severs sjogren spastic spasticity spastin spatially spg1 spg4 temporally tubulation
Tagcloud (Intersection) ?