PLA2G4C and S100A10

Number of citations: 0 (PubMedID 9202034)
Data Source: BioGRID (pull down)

		PLA2G4C	S100A10
Name		phospholipase A2 group IVC	S100 calcium binding protein A10
Structure		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Cell Cortex Membrane Mitochondrial Membrane	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding O-acyltransferase Activity Phospholipase A1 Activity Transferase Activity Hydrolase Activity Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Platelet Activating Factor Biosynthetic Process Inflammatory Response Parturition Phospholipid Catabolic Process Arachidonate Metabolic Process Intracellular Signal Transduction Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Glycerophospholipid Catabolic Process Lipid Droplet Formation	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PI Hydrolysis of LPC Hydrolysis of LPE	Dissolution of Fibrin Clot
Drugs		None	Phenethyl Isothiocyanate
GWAS		No GWAS studies recorded	Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )
Interacting Genes		2 interacting genes: APP S100A10	23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT
Entrez ID		8605	6281
HPRD ID		04673	00232
Ensembl ID		ENSG00000105499	ENSG00000197747
Uniprot IDs		Q9UP65	P60903
PDB IDs		Not available	1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
GO Terms Enriched among Interactors		Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Regulation Of Cell Junction Assembly Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization AnxA2-p11 Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Proteolysis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Plasma Membrane Repair Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Regulation Of Plasma Membrane Repair Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Plasminogen Activation Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Vesicle-mediated Transport Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation	Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding