PLA2G4C

Description		phospholipase A2 group IVC
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Cell Cortex Membrane Mitochondrial Membrane
	Molecular Function	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding O-acyltransferase Activity Phospholipase A1 Activity Transferase Activity Hydrolase Activity Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Platelet Activating Factor Biosynthetic Process Inflammatory Response Parturition Phospholipid Catabolic Process Arachidonate Metabolic Process Intracellular Signal Transduction Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Glycerophospholipid Catabolic Process Lipid Droplet Formation
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PI Hydrolysis of LPC Hydrolysis of LPE
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: APP S100A10
Entrez ID		8605
HPRD ID		04673
Ensembl ID		ENSG00000105499
Uniprot IDs		Q9UP65
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Regulation Of Cell Junction Assembly Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization AnxA2-p11 Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Proteolysis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Plasma Membrane Repair Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Regulation Of Plasma Membrane Repair Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Plasminogen Activation Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Vesicle-mediated Transport Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation
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