AP3B1 and AP3S2

Number of citations of the paper that reports this interaction (PMID 9182526)
38

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		AP3B1	AP3S2
Gene Name		adaptor-related protein complex 3, beta 1 subunit	adaptor-related protein complex 3, sigma 2 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Golgi Apparatus Membrane AP-3 Adaptor Complex Clathrin-coated Vesicle Membrane	Golgi Apparatus AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Phosphatase Binding GTP-dependent Protein Binding	Protein Transporter Activity
	Biological Process	Protein Targeting To Lysosome Intracellular Protein Transport Blood Coagulation Anterograde Axon Cargo Transport Melanosome Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation	Intracellular Protein Transport Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Insulin resistance/response ( 21901158)	Type 2 diabetes ( 21874001)
Protein-Protein Interactions		10 interactors: AP3S2 ARF1 ARF5 ARF6 ARR3 BUB1 BUB1B CLTC CSNK1A1 SLC30A3	6 interactors: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4
Entrez ID		8546	10239
HPRD ID		04551	03880
Ensembl ID		ENSG00000132842	ENSG00000157823
Uniprot IDs		E5RJ68 O00203	P59780
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Mitotic Nuclear Division Cell Division Protein Localization Regulation Of Cellular Component Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Transport Cell Cycle Mitotic Cell Cycle Process Negative Regulation Of Chromosome Segregation Protein Transport Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Mitotic Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Organelle Organization Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-Golgi Vesicle-mediated Transport Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Organelle Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Cellular Protein Localization Cellular Localization Small GTPase Mediated Signal Transduction Mitotic Cell Cycle Checkpoint Endocytosis Regulation Of Sequestering Of Zinc Ion Regulation Of Endocytosis Regulation Of Proteasomal Protein Catabolic Process Establishment Of Vesicle Localization Myeloid Cell Apoptotic Process Regulation Of Chromosome Organization Vesicle Localization	Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Axon Cargo Transport Establishment Of Organelle Localization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Organelle Localization Synaptic Vesicle Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Melanosome Organization Pigment Granule Organization Vesicle Organization Microtubule-based Process Protein Localization Antigen Processing And Presentation Microtubule-based Movement Positive Regulation Of Alpha-beta T Cell Differentiation Cellular Localization Cellular Pigmentation Cellular Protein Localization Signaling Positive Regulation Of T Cell Differentiation Protein Localization To Organelle Cell Communication Movement Of Cell Or Subcellular Component Organelle Organization Intracellular Transport Positive Regulation Of Lymphocyte Differentiation Synaptic Transmission Pigmentation Regulation Of T Cell Differentiation Synaptic Vesicle Membrane Organization Regulation Of Lymphocyte Differentiation Establishment Of Localization In Cell Regulation Of Endocytosis Eye Pigment Biosynthetic Process Cell-cell Signaling Intracellular Protein Transport Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Sequestering Of Zinc Ion Multi-ciliated Epithelial Cell Differentiation Positive Regulation Of Cell-cell Adhesion Eye Pigmentation
Tagcloud ?		amd3100 bl bortezomib c57bl6 canine cathepsin cbcs cfu cfus ch counts cyclic cyclophosphamide dilution elastase gemm granulocyte granulopoiesis hermansky hps lin lsk mobilization myeloperoxidase neutropenia neutropenic pearl pudlak sca
Tagcloud (Difference) ?		amd3100 bl bortezomib c57bl6 canine cathepsin cbcs cfu cfus ch counts cyclic cyclophosphamide dilution elastase gemm granulocyte granulopoiesis hermansky hps lin lsk mobilization myeloperoxidase neutropenia neutropenic pearl pudlak sca
Tagcloud (Intersection) ?