CGGBP1 and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		CGGBP1	SUV39H2
Description		CGG triplet repeat binding protein 1	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	DNA Binding Double-stranded DNA Binding Protein Binding Identical Protein Binding DNA-binding Transcription Factor Binding	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Epigenetic Regulation Of Gene Expression	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hand grip strength ( 29691431) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Red blood cell count ( 32888494) Walking pace ( 33128006)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		20 interacting genes: AKT1 BOLA2 BOLA2B CDC37 CDKN2D CEBPA FAM124A GLRX3 GORASP2 NTAQ1 PAX6 PIAS2 PICK1 PLEKHF2 POLR1C REL SDCBP SUV39H2 TXN2 UBE3A	43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57
Entrez ID		8545	79723
HPRD ID		04529	07580
Ensembl ID		ENSG00000163320	ENSG00000152455
Uniprot IDs		Q9UFW8	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?		Iron-sulfur Cluster Assembly Complex Cell Redox Homeostasis [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Chemical Homeostasis Homeostatic Process Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding HMG Box Domain Binding Transcription By RNA Polymerase I Response To Nutrient Levels Kinase Binding 2 Iron, 2 Sulfur Cluster Binding Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Regulation Of Ubiquitin-dependent Protein Catabolic Process Integrated Stress Response Signaling Regulation Of TRNA Methylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Interleukin-5 Receptor Complex Cellular Homeostasis Sperm Entry Intracellular Monoatomic Ion Homeostasis Intracellular Monoatomic Cation Homeostasis Positive Regulation Of Golgi Lumen Acidification Protein-N-terminal Glutamine Amidohydrolase Activity	Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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