CGGBP1 and TXN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CGGBP1	TXN2
Description		CGG triplet repeat binding protein 1	thioredoxin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleolus Mitochondrion Mitochondrial Matrix
	Molecular Function	DNA Binding Double-stranded DNA Binding Protein Binding Identical Protein Binding DNA-binding Transcription Factor Binding	Protein Binding Protein-disulfide Reductase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Epigenetic Regulation Of Gene Expression	Cell Redox Homeostasis
Pathways			Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Hand grip strength ( 29691431) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Red blood cell count ( 32888494) Walking pace ( 33128006)
Interacting Genes		20 interacting genes: AKT1 BOLA2 BOLA2B CDC37 CDKN2D CEBPA FAM124A GLRX3 GORASP2 NTAQ1 PAX6 PIAS2 PICK1 PLEKHF2 POLR1C REL SDCBP SUV39H2 TXN2 UBE3A	78 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32
Entrez ID		8545	25828
HPRD ID		04529	07161
Ensembl ID		ENSG00000163320	ENSG00000100348
Uniprot IDs		Q9UFW8	Q99757
PDB IDs			1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Iron-sulfur Cluster Assembly Complex Cell Redox Homeostasis [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Chemical Homeostasis Homeostatic Process Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding HMG Box Domain Binding Transcription By RNA Polymerase I Response To Nutrient Levels Kinase Binding 2 Iron, 2 Sulfur Cluster Binding Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Regulation Of Ubiquitin-dependent Protein Catabolic Process Integrated Stress Response Signaling Regulation Of TRNA Methylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Interleukin-5 Receptor Complex Cellular Homeostasis Sperm Entry Intracellular Monoatomic Ion Homeostasis Intracellular Monoatomic Cation Homeostasis Positive Regulation Of Golgi Lumen Acidification Protein-N-terminal Glutamine Amidohydrolase Activity	Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process
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