PPFIBP1 and PPFIA2

Number of citations of the paper that reports this interaction (PubMedID 9624153)
0

Data Source:
HPRD (in vivo, in vitro)

		PPFIBP1	PPFIA2
Description		PPFIB scaffold protein 1	PPFI scaffold protein A2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Cell Cortex Presynaptic Active Zone	Cytoplasm Cytosol Synaptic Vesicle Cell Surface Postsynaptic Density Axon Presynaptic Membrane Cell Projection Dendritic Spine Synapse Presynaptic Active Zone Extracellular Exosome Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Structural Constituent Of Postsynaptic Density Structural Constituent Of Presynapse
	Biological Process	Cell Adhesion Neuromuscular Junction Development Cortical Microtubule Organization	Cell-matrix Adhesion Synapse Organization Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Presynapse Organization Dense Core Granule Cytoskeletal Transport Maintenance Of Postsynaptic Density Structure Regulation Of Synaptic Vesicle Exocytosis
Pathways		Receptor-type tyrosine-protein phosphatases Signaling by ALK fusions and activated point mutants	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		Cerebral cortical growth ( 29682794) Early-onset Parkinson's disease ( 28256260) Femur bone mineral density x serum urate levels interaction ( 34046847) Refractive error ( 32231278)	Age-related cataracts (age at onset) ( 25352737) Alcohol dependence ( 26365420) Delirium ( 29631748) Femur bone mineral density x serum urate levels interaction ( 34046847) Lean body mass ( 28552196) Post bronchodilator FEV1 ( 26634245) Resting heart rate ( 27798624) Schizophrenia ( 22885689)
Interacting Genes		8 interacting genes: PBX2 PPFIA1 PPFIA2 PPFIA3 PTPRM S100A4 TTC3 YWHAG	15 interacting genes: CAST CDC5L ERC2 GIT1 ITSN1 MTDH PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS SMARCA2 TSC1
Entrez ID		8496	8499
HPRD ID		04390	04392
Ensembl ID		ENSG00000110841	ENSG00000139220
Uniprot IDs		Q86W92	B7Z7Y5 G3V200 H0YHK3 O75334
PDB IDs			3TAC 3TAD 6IUH 7D2E 7D2G 7D2H
Enriched GO Terms of Interacting Partners?		Presynaptic Active Zone Synapse Organization	Synapse Organization Presynaptic Active Zone Cell Junction Organization Synaptic Membrane Adhesion Presynaptic Membrane Glutamatergic Synapse Regulation Of Dendritic Spine Development Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Cortical Microtubule Organization Presynaptic Active Zone Organization Regulation Of Organelle Organization Presynaptic Active Zone Cytoplasmic Component Schaffer Collateral - CA1 Synapse Protein Tyrosine Phosphatase Activity Regulation Of Postsynaptic Density Assembly Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Activity Regulation Of Cellular Component Organization Regulation Of Postsynaptic Specialization Assembly Regulation Of Excitatory Synapse Assembly Peptidyl-tyrosine Dephosphorylation Neuron Projection Regulation Of Postsynapse Organization Phosphoprotein Phosphatase Activity Regulation Of Axon Regeneration Growth Cone Regulation Of Neuron Projection Regeneration Maintenance Of Synapse Structure Regulation Of Response To Wounding Neuromuscular Junction Development Cell Cortex Positive Regulation Of Dendritic Spine Development Lamellipodium Calcium-dependent Cysteine-type Endopeptidase Inhibitor Activity Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Modulation Of Chemical Synaptic Transmission Chondroitin Sulfate Proteoglycan Binding Memory T Cell Differentiation Cortical Cytoskeleton Organization Epididymosome Negative Regulation Of ARF Protein Signal Transduction Cell Junction Maintenance Synapse Presynapse Nervous System Development Postsynaptic Density Cytoplasmic Microtubule Organization Regulation Of Cell Junction Assembly Clathrin-dependent Synaptic Vesicle Endocytosis Cellular Component Maintenance
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