PPIL4 and CHERP

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		PPIL4	CHERP
Description		peptidylprolyl isomerase like 4	calcium homeostasis endoplasmic reticulum protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Nucleic Acid Binding RNA Binding Protein Binding Transmembrane Transporter Binding
	Biological Process		RNA Processing Intracellular Calcium Ion Homeostasis Nervous System Development Negative Regulation Of Cell Population Proliferation Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Rheumatoid arthritis ( 24390342 30423114) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: CHERP DLG2 PAX6 RBFOX2 SMAD5	48 interacting genes: ADAMTSL4 AGGF1 APBB1 ARGLU1 C1orf94 CCAR1 CLK3 EWSR1 FASTK FIGN FRA10AC1 HNRNPH3 KRTAP11-1 LASP1 LUC7L MAGED1 MECOM MIR106B MIR200C MIR363 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7E MIRLET7G MIRLET7I PPIL4 PRPF38A PRPF40A RACK1 RBFOX2 RBM23 RBM39 RBM7 RNPS1 SART1 SAXO1 SF3B4 SNRNP27 SNRNP70 SORBS3 SRPK1 SRPK2 TLE3 TTC14 U2AF1 USP54 WBP4
Entrez ID		85313	10523
HPRD ID		07606	13051
Ensembl ID		ENSG00000131013	ENSG00000085872
Uniprot IDs		Q8WUA2	Q8IWX8
PDB IDs		7QTT 8CH6 8I0S 8I0T 8I0U 8I0V
Enriched GO Terms of Interacting Partners?		Nervous System Development System Development Forebrain-midbrain Boundary Formation Pancreatic A Cell Development GMP Kinase Activity Retrograde Axonal Protein Transport Anterograde Axonal Protein Transport Developmental Process Regulation Of Fas Signaling Pathway Heteromeric SMAD Protein Complex Anti-Mullerian Hormone Receptor Signaling Pathway Negative Regulation Of Fas Signaling Pathway Mullerian Duct Regression Osteoblast Fate Commitment Chemical Homeostasis Cell Fate Commitment SMAD Protein Complex DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DEAD/H-box RNA Helicase Binding Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Type B Pancreatic Cell Differentiation Forebrain Neuron Fate Commitment Habenula Development Oligodendrocyte Cell Fate Specification Ventral Spinal Cord Development Pallium Development Formation Of Anatomical Boundary Iris Morphogenesis Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization Juxtaparanode Region Of Axon GDP Metabolic Process Cellular Response To Potassium Ion Protein Transport Along Microtubule Negative Regulation Of DNA-templated Transcription Anatomical Structure Regression Ubiquitin Protein Ligase Binding Homeostatic Process Negative Regulation Of RNA Biosynthetic Process Dorsal/ventral Axis Specification HMG Box Domain Binding Co-SMAD Binding Regulation Of Timing Of Cell Differentiation Cornea Development In Camera-type Eye Salivary Gland Morphogenesis Regulation Of Development, Heterochronic	RNA Splicing MRNA Processing Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions RNA Binding Regulation Of MRNA Splicing, Via Spliceosome MiRNA-mediated Post-transcriptional Gene Silencing Nucleic Acid Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Nuclear Speck Regulation Of MRNA Processing RISC Complex Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RNA Metabolic Process Spliceosomal Complex RS Domain Binding U1 SnRNP Binding Post-transcriptional Regulation Of Gene Expression Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process MRNA Cis Splicing, Via Spliceosome U2-type Precatalytic Spliceosome U2-type Prespliceosome Negative Regulation Of Macromolecule Biosynthetic Process U1 SnRNP Precatalytic Spliceosome Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Nucleoplasm Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Extracellular Vesicle Nucleobase-containing Compound Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Stability Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Negative Regulation Of Gene Expression
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