UBL7 and CD4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UBL7	CD4
Gene Name		ubiquitin-like 7	CD4 molecule
Image
Gene Ontology Annotations	Cellular Component		Early Endosome Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane T Cell Receptor Complex Membrane Raft
	Molecular Function		Glycoprotein Binding Receptor Activity Transmembrane Signaling Receptor Activity Extracellular Matrix Structural Constituent Protein Binding Zinc Ion Binding Coreceptor Activity Enzyme Binding Protein Kinase Binding MHC Class II Protein Binding Protein Homodimerization Activity
	Biological Process		Cytokine Production Induction By Virus Of Host Cell-cell Fusion Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Viral Process T Cell Differentiation Entry Into Host Cell T Cell Costimulation Maintenance Of Protein Location In Cell T Cell Selection Positive Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Protein Palmitoleylation Positive Regulation Of Protein Kinase Activity Regulation Of Defense Response To Virus By Virus Positive Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response To Gram-negative Bacterium Positive Regulation Of Calcium-mediated Signaling T Cell Receptor Signaling Pathway Regulation Of T Cell Activation
Pathways			Vpu mediated degradation of CD4 Downstream TCR signaling Generation of second messenger molecules Translocation of ZAP-70 to Immunological synapse Costimulation by the CD28 family Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Early Phase of HIV Life Cycle HIV Life Cycle TCR signaling Alpha-defensins PD-1 signaling Defensins Phosphorylation of CD3 and TCR zeta chains Nef Mediated CD4 Down-regulation Binding and entry of HIV virion Innate Immune System Adaptive Immune System
Drugs
Diseases
GWAS			Response to Vitamin E supplementation ( 22437554)
Protein-Protein Interactions		8 interactors: AP1G1 BAG6 CAPN7 CD4 ERCC1 RAD23A UBC VBP1	38 interactors: ABCB1 ADRB2 CCR5 CD2 CD28 CD38 CD44 CD5 CD53 CD82 CTSD CXCL12 CXCR4 DPP4 FCGR3A HLA-DPA1 HLA-DQA2 HLA-DQB1 IL16 IL2RA INPPL1 KCNAB2 LAT LCK LGALS1 MAPK14 MARCH4 PI4KA PIK3R1 PIP PTPRC SELL SIVA1 SPG21 TFRC TNFRSF10A UBL7 UNC119
Entrez ID		84993	920
HPRD ID		16556	01740
Ensembl ID		ENSG00000138629	ENSG00000010610
Uniprot IDs		D3DW56 Q96S82	B0AZV7 B4DT49 P01730
PDB IDs		2CWB 2DEN	1CDH 1CDI 1CDJ 1CDU 1CDY 1G9M 1G9N 1GC1 1JL4 1OPN 1OPT 1OPW 1Q68 1RZJ 1RZK 1WBR 1WIO 1WIP 1WIQ 2B4C 2JKR 2JKT 2KLU 2NXY 2NXZ 2NY0 2NY1 2NY2 2NY3 2NY4 2NY5 2NY6 2QAD 3B71 3CD4 3JWD 3JWO 3LQA 3O2D 3S4S 3S5L 3T0E 4JM2
Enriched GO Terms of Interacting Partners?		Viral Process Regulation Of Defense Response To Virus By Virus Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Immune System Process Regulation Of Defense Response To Virus Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Natural Killer Cell Degranulation Cellular Protein Catabolic Process DNA Repair Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Response To Stress Proteolysis Positive Regulation Of Immune Response Post-embryonic Hemopoiesis Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Golgi To Lysosome Transport Regulation Of Proteolysis Pyrimidine Dimer Repair By Nucleotide-excision Repair Positive Regulation Of Innate Immune Response Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Endosomal Transport Nucleotide-excision Repair, DNA Incision Tail-anchored Membrane Protein Insertion Into ER Membrane Replicative Cell Aging Membrane Organization Regulation Of Immune Response Response To Stress Regulation Of Cellular Protein Metabolic Process Golgi To Vacuole Transport Interstrand Cross-link Repair Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Immune System Process Endosome To Melanosome Transport Protein Insertion Into ER Membrane Pigment Granule Maturation Protein Metabolic Process Regulation Of Innate Immune Response	Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Immune System Process Regulation Of Immune System Process Regulation Of T Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Positive Regulation Of Cell-cell Adhesion T Cell Costimulation Regulation Of Cell Activation Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Antigen Receptor-mediated Signaling Pathway Positive Regulation Of T Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Stimulus Immune Response-regulating Signaling Pathway T Cell Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune Response Signaling Immune Response Cell Communication Signal Transduction Cell Surface Receptor Signaling Pathway Lymphocyte Activation Leukocyte Aggregation Cellular Response To Stimulus Apoptotic Process Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Programmed Cell Death Response To Stress Leukocyte Migration Leukocyte Activation Cell Death Death Cell Activation Defense Response Homeostatic Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Locomotion Cell Migration Cell Motility Single Organismal Cell-cell Adhesion Cellular Chemical Homeostasis
Tagcloud ?			allergen asthmatics box caat cd18 chemotactic coactivator complexity concert consists dyad exons ga gabp gabpalpha harbor inducible introns lymphocytes mast motifs posttranslational pro processed remote share supplementing symmetry tata tightly
Tagcloud (Difference) ?			allergen asthmatics box caat cd18 chemotactic coactivator complexity concert consists dyad exons ga gabp gabpalpha harbor inducible introns lymphocytes mast motifs posttranslational pro processed remote share supplementing symmetry tata tightly
Tagcloud (Intersection) ?