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UBL7 and ERCC1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
HPRD
(two hybrid)
UBL7
ERCC1
Description
ubiquitin like 7
ERCC excision repair 1, endonuclease non-catalytic subunit
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Nucleotide-excision Repair Complex
Nucleotide-excision Repair Factor 1 Complex
Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Cytoplasm
ERCC4-ERCC1 Complex
Molecular Function
Protein Binding
Protein-macromolecule Adaptor Activity
Polyubiquitin Modification-dependent Protein Binding
Single-stranded DNA Endodeoxyribonuclease Activity
TFIID-class Transcription Factor Complex Binding
DNA Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
3' Overhang Single-stranded DNA Endodeoxyribonuclease Activity
Promoter-specific Chromatin Binding
Biological Process
Immune System Process
Ubiquitin-dependent Protein Catabolic Process
Protein K27-linked Ubiquitination
Innate Immune Response
Defense Response To Virus
Antiviral Innate Immune Response
Pyrimidine Dimer Repair By Nucleotide-excision Repair
Telomere Maintenance
DNA Repair
Nucleotide-excision Repair
Double-strand Break Repair
Double-strand Break Repair Via Nonhomologous End Joining
DNA Recombination
Mitotic Recombination
Syncytium Formation
DNA Damage Response
Response To Oxidative Stress
Germ Cell Development
Spermatogenesis
Cell Population Proliferation
Determination Of Adult Lifespan
Male Gonad Development
UV Protection
Response To X-ray
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance
Post-embryonic Hemopoiesis
Multicellular Organism Growth
Interstrand Cross-link Repair
Isotype Switching
Insulin-like Growth Factor Receptor Signaling Pathway
Cell Development
Oogenesis
Chromosome Organization
Positive Regulation Of Transcription Initiation By RNA Polymerase II
Telomeric DNA-containing Double Minutes Formation
UV-damage Excision Repair
Replicative Senescence
T-circle Formation
Positive Regulation Of T-circle Formation
Negative Regulation Of Protection From Non-homologous End Joining At Telomere
Pathways
HDR through Single Strand Annealing (SSA)
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Fanconi Anemia Pathway
Drugs
Diseases
Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
GWAS
Craniofacial microsomia (
26853712
)
Eosinophil percentage of white cells (
32888494
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Metabolite levels (
23823483
)
Alzheimer's disease or HDL levels (pleiotropy) (
30805717
)
Body mass index (
26426971
)
Body mass index (age>50) (
26426971
)
Body mass index x age interaction (
26426971
)
Body mass index x sex x age interaction (4df test) (
26426971
)
Simvastatin-induced myopathy (
31220337
)
Interacting Genes
17 interacting genes:
AP1G1
BAG6
CAPN7
CD4
CDKN2A
ERCC1
ESRRG
IDH1
MFHAS1
MYBPH
NEDD8
RAD23A
RXRB
SH3GLB1
UBC
VBP1
WWP2
19 interacting genes:
APP
CHRM5
DRC4
ERCC4
KIF11
MKRN3
PDE9A
RAD52
RPA1
RPA2
RPA3
SLX1A
TRMT2B
UBL7
UHRF1
USHBP1
USP45
VPS37B
XPA
Entrez ID
84993
2067
HPRD ID
16556
00533
Ensembl ID
ENSG00000138629
ENSG00000012061
Uniprot IDs
Q96S82
P07992
PDB IDs
2CWB
2DEN
1Z00
2A1I
2A1J
2JNW
2JPD
2MUT
6SXA
6SXB
Enriched GO Terms of Interacting Partners
?
Replicative Senescence
Retinoic Acid Receptor Signaling Pathway
Nuclear Steroid Receptor Activity
Ubiquitin Protein Ligase Binding
Modification-dependent Protein Catabolic Process
Protein Tag Activity
Proteasome Binding
Ubiquitin-specific Protease Binding
Macromolecule Catabolic Process
Regulation Of Protein Stability
Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteolysis
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Proteolysis
Polyubiquitin Modification-dependent Protein Binding
Nucleotide-excision Repair
Recombinational Repair
Double-strand Break Repair Via Homologous Recombination
DNA Replication Factor A Complex
DNA Repair
Double-strand Break Repair
DNA Recombination
Damaged DNA Binding
DNA Metabolic Process
Telomere Maintenance
DNA Damage Response
Base-excision Repair
Single-stranded DNA Binding
Telomere Organization
Nucleotide-excision Repair Involved In Interstrand Cross-link Repair
Chromosome Organization
Nucleotide-excision Repair Factor 1 Complex
Mismatch Repair
Cellular Response To Stress
Nucleic Acid Metabolic Process
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Nucleobase-containing Compound Metabolic Process
G-rich Strand Telomeric DNA Binding
UV Protection
Macromolecule Metabolic Process
Organelle Organization
Mitotic Recombination
Site Of Double-strand Break
Response To Stress
Positive Regulation Of Long-term Synaptic Potentiation
DNA Double-strand Break Processing
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Telomere Maintenance Via Telomere Lengthening
DNA Replication
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Regulation Of Long-term Synaptic Potentiation
Negative Regulation Of Telomere Maintenance
Chromosome, Telomeric Region
Double-strand Break Repair Via Single-strand Annealing
Nucleotide-excision Repair, DNA Damage Recognition
Histone H3 Ubiquitin Ligase Activity
RRNA (uridine-C5-)-methyltransferase Activity
Mitotic Spindle Assembly
Regulation Of CAMP/PKA Signal Transduction
DNA Binding
Regulation Of Telomere Maintenance Via Telomere Lengthening
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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