ERCC1 and TRMT2B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ERCC1	TRMT2B
Gene Name		excision repair cross-complementation group 1	tRNA methyltransferase 2 homolog B (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleotide-excision Repair Complex Nucleotide-excision Repair Factor 1 Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Transcription Factor TFIID Complex Cytoplasm	Mitochondrion
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity TFIID-class Transcription Factor Binding Damaged DNA Binding Single-stranded DNA Binding Protein Binding Protein C-terminus Binding TBP-class Protein Binding Protein Domain Specific Binding Structure-specific DNA Binding	S-adenosylmethionine-dependent TRNA (m5U54) Methyltransferase Activity
	Biological Process	Nucleotide-excision Repair, DNA Damage Removal Pyrimidine Dimer Repair By Nucleotide-excision Repair DNA Catabolic Process, Endonucleolytic Replicative Cell Aging DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Double-strand Break Repair DNA Recombination Mitotic Recombination Syncytium Formation Response To Oxidative Stress Spermatogenesis Response To Nutrient Cell Proliferation Male Gonad Development UV Protection Response To Sucrose Response To X-ray Multicellular Organismal Aging Negative Regulation Of Telomere Maintenance Post-embryonic Hemopoiesis Multicellular Organism Growth Interstrand Cross-link Repair Isotype Switching Oogenesis Embryonic Organ Development Chromosome Organization	RNA Methylation TRNA Processing
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Transcription-coupled NER (TC-NER) Formation of incision complex in GG-NER Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in GG-NER Dual incision reaction in TC-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ERCC4 MKRN3 SLX1A TRMT2B UBL7 USHBP1 VPS37B XPA	1 interactors: ERCC1
Entrez ID		2067	79979
HPRD ID		00533	06520
Ensembl ID		ENSG00000012061	ENSG00000188917
Uniprot IDs		P07992	F2Z384 Q96GJ1
PDB IDs		1Z00 2A1I 2A1J 2JNW 2JPD
Enriched GO Terms of Interacting Partners?		DNA Catabolic Process Nucleotide-excision Repair, DNA Damage Removal Aromatic Compound Catabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Catabolic Process, Endonucleolytic Nucleotide-excision Repair Nucleotide-excision Repair Involved In Interstrand Cross-link Repair DNA Repair Response To UV Double-strand Break Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Incision, 3'-to Lesion DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Telomere Maintenance Via Telomere Shortening DNA Recombination DNA Metabolic Process Nucleotide-excision Repair, DNA Incision DNA Double-strand Break Processing Interstrand Cross-link Repair Negative Regulation Of Telomere Maintenance Nucleic Acid Phosphodiester Bond Hydrolysis Viral Protein Processing Response To Light Stimulus Resolution Of Meiotic Recombination Intermediates UV Protection Cellular Response To Stress Regulation Of Telomere Maintenance Response To Radiation Chromosome Separation Virion Assembly TRNA Methylation Intracellular Transport Of Virus Catabolic Process DNA Catabolic Process, Exonucleolytic Transcription-coupled Nucleotide-excision Repair Reciprocal Meiotic Recombination Nucleobase-containing Compound Metabolic Process RNA Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process TRNA Modification Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Meiotic Chromosome Segregation Negative Regulation Of Chromosome Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of DNA Metabolic Process	Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Incision, 3'-to Lesion Post-embryonic Hemopoiesis Pyrimidine Dimer Repair By Nucleotide-excision Repair Replicative Cell Aging Nucleotide-excision Repair, DNA Incision Interstrand Cross-link Repair Negative Regulation Of Telomere Maintenance Pyrimidine Dimer Repair UV Protection Response To Sucrose Nucleotide-excision Repair, DNA Damage Removal Regulation Of Telomere Maintenance Isotype Switching Mitotic Recombination Response To X-ray Syncytium Formation Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Multicellular Organismal Aging Transcription-coupled Nucleotide-excision Repair Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response B Cell Activation Involved In Immune Response Immunoglobulin Production Cell Aging Oogenesis Negative Regulation Of Chromosome Organization Nucleotide-excision Repair DNA Catabolic Process, Endonucleolytic Negative Regulation Of DNA Metabolic Process Female Gamete Generation Multicellular Organism Growth Response To UV Post-embryonic Development DNA Catabolic Process Response To Ionizing Radiation Double-strand Break Repair Leukocyte Activation Involved In Immune Response B Cell Activation Male Gonad Development Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Response To Carbohydrate Male Sex Differentiation Regulation Of Chromosome Organization Response To Nutrient Gonad Development DNA Recombination Development Of Primary Sexual Characteristics Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Tagcloud ?		3b aa8 adp antiapoptotic became carrying cho concordance confer delay determinant ercc3 erk2 excision g5 hamster mtt ner ovary pair parental phosphatidylinositol pi player repair ribose uv24 withdrawal xpb
Tagcloud (Difference) ?		3b aa8 adp antiapoptotic became carrying cho concordance confer delay determinant ercc3 erk2 excision g5 hamster mtt ner ovary pair parental phosphatidylinositol pi player repair ribose uv24 withdrawal xpb
Tagcloud (Intersection) ?