TBRG1 and SMYD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TBRG1	SMYD1
Description		transforming growth factor beta regulator 1	SET and MYND domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Transcription Corepressor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone H3K4 Methyltransferase Activity Metal Ion Binding Histone H3K4 Trimethyltransferase Activity
	Biological Process	DNA Replication Negative Regulation Of Cell Population Proliferation Protein Stabilization Regulation Of Cell Cycle Protein Localization To Nucleoplasm	Chromatin Remodeling Heart Development Positive Regulation Of Myotube Differentiation Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of DNA-templated Transcription
Pathways			Cardiogenesis
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715)	Night sleep phenotypes ( 27126917) Retinal detachment or retinal break ( 31816047)
Interacting Genes		9 interacting genes: CCDC136 CDKN2A EXOSC8 INO80E RALBP1 RUNDC3A SLC13A1 SMYD1 ZMYND19	45 interacting genes: ARID5A BACH2 BHLHE40 C11orf16 CCDC33 CFAP263 CFAP68 CFTR CIMIP2A DISC1 DVL1 FAM204A FAM83A FAM86C1P H3-5 HDAC2 HDAC3 HDHD3 HMG20A HOMEZ KIF16B KRT35 LENG8 MDFI MEOX2 MYH7B NACA NEFL OGDHL PATZ1 POU2AF2 POU6F2 PRR22 RBM4B RSPH6A RUSC1 SNX11 SPAG8 TBRG1 TTC33 USP54 UTP14A WDR77 ZBTB3 ZBTB44
Entrez ID		84897	150572
HPRD ID		15477	06025
Ensembl ID		ENSG00000154144	ENSG00000115593
Uniprot IDs		Q3YBR2	E9PHG3 Q8NB12
PDB IDs		2WZO
Enriched GO Terms of Interacting Partners?			Circadian Regulation Of Gene Expression Protein Decrotonylase Activity Histone Decrotonylase Activity Protein De-2-hydroxyisobutyrylase Activity Protein Lysine Delactylase Activity Axonemal A Tubule Inner Sheath Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Deacetylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Sperm Flagellum Cilium Movement Involved In Cell Motility Circadian Rhythm Protein Lysine Deacetylase Activity Microtubule-based Movement
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