TBRG1 and CCDC136

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TBRG1	CCDC136
Gene Name		transforming growth factor beta regulator 1	coiled-coil domain containing 136
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Mitochondrion Integral Component Of Membrane
	Molecular Function	Protein Binding
	Biological Process	DNA Replication Cell Cycle Arrest Negative Regulation Of Cell Proliferation Nucleolus To Nucleoplasm Transport Protein Stabilization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CCDC136 CDKN2A INO80E RALBP1 RUNDC3A	62 interactors: ABT1 AQP1 ASB7 ATP5O ATXN1 BARD1 BLOC1S6 BYSL C19orf66 C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZSCAN26
Entrez ID		84897	64753
HPRD ID		15477	10887
Ensembl ID			ENSG00000128596
Uniprot IDs		Q3YBR2	Q96JN2
PDB IDs		2WZO
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Positive Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Macrophage Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Cell Aging Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Guanylate Cyclase Activity Intracellular Signal Transduction Heterochromatin Assembly Positive Regulation Of Protein Sumoylation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Smooth Muscle Cell Apoptotic Process Heterochromatin Organization Regulation Of Macrophage Apoptotic Process Replicative Senescence Positive Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of Cdc42 GTPase Activity Negative Regulation Of B Cell Proliferation Positive Regulation Of CGMP Metabolic Process Regulation Of Protein Sumoylation Regulation Of CGMP Biosynthetic Process Regulation Of Catalytic Activity Protein Destabilization Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Senescence Regulation Of Cdc42 GTPase Activity Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Somatic Stem Cell Division Cellular Senescence Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Export From Nucleus Regulation Of CGMP Metabolic Process Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Leukocyte Apoptotic Process Protein K63-linked Ubiquitination Negative Regulation Of T Cell Differentiation Cellular Response To Stimulus Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of B Cell Activation Regulation Of Myeloid Cell Apoptotic Process Stem Cell Division Regulation Of Signal Transduction By P53 Class Mediator Regulation Of G2/M Transition Of Mitotic Cell Cycle	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Chromatin Organization Chromatin Modification Cellular Metabolic Process Organelle Organization Cell Cycle Regulation Of Cellular Process Chromosome Organization Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Chromatin Remodeling Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Protein Sumoylation Regulation Of Cell Cycle Signal Transduction In Response To DNA Damage Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Catabolic Process Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host 'de Novo' Actin Filament Nucleation Transepithelial Water Transport Cardiac Muscle Thin Filament Assembly
Tagcloud ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine
Tagcloud (Difference) ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine
Tagcloud (Intersection) ?