TBRG1 and INO80E

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TBRG1	INO80E
Gene Name		transforming growth factor beta regulator 1	INO80 complex subunit E
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nucleolus Ino80 Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Replication Cell Cycle Arrest Negative Regulation Of Cell Proliferation Nucleolus To Nucleoplasm Transport Protein Stabilization	DNA Replication DNA Repair DNA Recombination Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CCDC136 CDKN2A INO80E RALBP1 RUNDC3A	11 interactors: FAM124A GEM IKBKG KPNA2 MORN4 NHLH1 PRKAA1 PSMA1 SDCBP TBRG1 TNFAIP8
Entrez ID		84897	283899
HPRD ID		15477	08816
Ensembl ID			ENSG00000169592
Uniprot IDs		Q3YBR2	J3KNE2 Q6Y2K3 Q8NBZ0
PDB IDs		2WZO
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Positive Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Macrophage Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Cell Aging Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Guanylate Cyclase Activity Intracellular Signal Transduction Heterochromatin Assembly Positive Regulation Of Protein Sumoylation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Smooth Muscle Cell Apoptotic Process Heterochromatin Organization Regulation Of Macrophage Apoptotic Process Replicative Senescence Positive Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of Cdc42 GTPase Activity Negative Regulation Of B Cell Proliferation Positive Regulation Of CGMP Metabolic Process Regulation Of Protein Sumoylation Regulation Of CGMP Biosynthetic Process Regulation Of Catalytic Activity Protein Destabilization Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Senescence Regulation Of Cdc42 GTPase Activity Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Somatic Stem Cell Division Cellular Senescence Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Export From Nucleus Regulation Of CGMP Metabolic Process Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Leukocyte Apoptotic Process Protein K63-linked Ubiquitination Negative Regulation Of T Cell Differentiation Cellular Response To Stimulus Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of B Cell Activation Regulation Of Myeloid Cell Apoptotic Process Stem Cell Division Regulation Of Signal Transduction By P53 Class Mediator Regulation Of G2/M Transition Of Mitotic Cell Cycle	Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Cell Cycle Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Establishment Of Localization In Cell Positive Regulation Of MAPK Cascade Negative Regulation Of Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Signal Transduction Viral Process Cellular Localization Positive Regulation Of Transferase Activity Cell Cycle Negative Regulation Of Glucose Import In Response To Insulin Stimulus Nucleolus To Nucleoplasm Transport Activation Of MAPK Activity Positive Regulation Of Cellular Metabolic Process Regulation Of MAPK Cascade Cell Cycle Arrest Regulation Of Apoptotic Process Response To Camptothecin Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Cell Death Regulation Of Cellular Process Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Sphingolipid Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAP Kinase Activity Regulation Of Ceramide Biosynthetic Process Cell Surface Receptor Signaling Pathway Response To External Stimulus Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Phosphorylation Intracellular Signal Transduction Positive Regulation Of Cholesterol Metabolic Process Cellular Response To Ethanol Positive Regulation Of Protein Modification Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Glucose Import Nuclear Transport Activation Of Protein Kinase Activity Substrate-dependent Cell Migration, Cell Extension Regulation Of Energy Homeostasis Positive Regulation Of Protein Serine/threonine Kinase Activity
Tagcloud ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine	apobec3 ash2l cbx1 cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Difference) ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine	apobec3 ash2l cbx1 cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Intersection) ?