TBRG1 and RALBP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TBRG1	RALBP1
Gene Name		transforming growth factor beta regulator 1	ralA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Cytosol Membrane
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding ATPase Activity Ral GTPase Binding Rac GTPase Activator Activity ATPase Activity, Coupled To Movement Of Substances Rac GTPase Binding
	Biological Process	DNA Replication Cell Cycle Arrest Negative Regulation Of Cell Proliferation Nucleolus To Nucleoplasm Transport Protein Stabilization	Transport Chemotaxis Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Rac GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Cdc42 GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CCDC136 CDKN2A INO80E RALBP1 RUNDC3A	27 interactors: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GPS2 GSE1 HOOK2 HSF1 IKBKG PPL PRKCA RAC1 RALA RALB REPS1 REPS2 SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 ZBTB38 ZNF707
Entrez ID		84897	10928
HPRD ID		15477	09013
Ensembl ID			ENSG00000017797
Uniprot IDs		Q3YBR2	Q15311
PDB IDs		2WZO	2KWH 2KWI
Enriched GO Terms of Interacting Partners?		Small GTPase Mediated Signal Transduction Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Positive Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Macrophage Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Cell Aging Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Guanylate Cyclase Activity Intracellular Signal Transduction Heterochromatin Assembly Positive Regulation Of Protein Sumoylation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Smooth Muscle Cell Apoptotic Process Heterochromatin Organization Regulation Of Macrophage Apoptotic Process Replicative Senescence Positive Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of Cdc42 GTPase Activity Negative Regulation Of B Cell Proliferation Positive Regulation Of CGMP Metabolic Process Regulation Of Protein Sumoylation Regulation Of CGMP Biosynthetic Process Regulation Of Catalytic Activity Protein Destabilization Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Senescence Regulation Of Cdc42 GTPase Activity Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Somatic Stem Cell Division Cellular Senescence Regulation Of Cdc42 Protein Signal Transduction Regulation Of Protein Export From Nucleus Regulation Of CGMP Metabolic Process Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Leukocyte Apoptotic Process Protein K63-linked Ubiquitination Negative Regulation Of T Cell Differentiation Cellular Response To Stimulus Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of B Cell Activation Regulation Of Myeloid Cell Apoptotic Process Stem Cell Division Regulation Of Signal Transduction By P53 Class Mediator Regulation Of G2/M Transition Of Mitotic Cell Cycle	Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Differentiation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Neurotrophin Signaling Pathway TRAIL-activated Apoptotic Signaling Pathway Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Regulation Of Cellular Localization Immune Response-regulating Signaling Pathway Response To External Stimulus Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Localization Viral Process Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Growth Factor Cellular Response To Stimulus Regulation Of Immune System Process Regulation Of Phosphorylation Positive Regulation Of Immune Response Signal Transduction Defense Response Cell Cycle Positive Regulation Of Metabolic Process Negative Regulation Of Intracellular Signal Transduction Protein Complex Assembly Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Myeloid Cell Differentiation
Tagcloud ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine	abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Difference) ?		adenoma arf cassette designation dissecting expansion galactosidase harderian helps hemangioma heterozygous homozygous hyperplasia interactor marginal mdm2 niam outstanding papillary predisposition pulp spleens splenic sum tip60 undefined unexpectedly unstudied uterine	abrogate complemented counteracts cytoplasmic downstream effectors equally gef hairpin kip1 lacks localization mislocalization mislocalizing murine note opposing overactivation p27 phospholipase pld1 rala ras ser thr transforming ways
Tagcloud (Intersection) ?