GEMIN2 and SRSF2

Number of citations of the paper that reports this interaction (PMID 9447963)
8

Data Source:
HPRD (two hybrid, in vitro)

		GEMIN2	SRSF2
Gene Name		gem (nuclear organelle) associated protein 2	serine/arginine-rich splicing factor 2
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm PML Body Nuclear Speck Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding Transcription Corepressor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Gene Expression NcRNA Metabolic Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		snRNP Assembly Metabolism of non-coding RNA	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: DDX20 DHX9 GEMIN5 IKBKG RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	33 interactors: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRSF1 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		8487	6427
HPRD ID		03999	02888
Ensembl ID		ENSG00000092208	ENSG00000161547
Uniprot IDs		O14893	Q01130 Q53FN0
PDB IDs		2LEH 3S6N	2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression DNA-templated Transcription, Termination MRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Cellular Nitrogen Compound Metabolic Process RNA Export From Nucleus Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport NcRNA Metabolic Process RNA Transport RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Transcription From RNA Polymerase II Promoter Establishment Of Localization In Cell Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Neutrophil Mediated Immunity Neutrophil Activation Cytoplasmic Transport Cellular Localization Positive Regulation Of RNA Splicing Leukocyte Degranulation Regulation Of MRNA Stability Regulated Secretory Pathway	RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Nuclear Export Spliceosomal Complex Assembly MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Nucleocytoplasmic Transport Nuclear Transport MRNA 3'-end Processing Regulation Of MRNA Processing RNA 3'-end Processing MRNA Transport RNA Transport Cellular Macromolecular Complex Assembly RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Cell Cycle Regulation Of RNA Splicing Regulation Of Cell Cycle Cytoplasmic Transport Cellular Metabolic Process Mitotic Cell Cycle Cell Cycle Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Intracellular Transport RNA Biosynthetic Process Mitotic Cell Cycle Process Negative Regulation Of Cell Cycle Cellular Component Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome DNA Strand Elongation Involved In DNA Replication Cellular Localization DNA Strand Elongation Regulation Of Protein Export From Nucleus
Tagcloud ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Difference) ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous	asxl1 biologic clonal cmml created cytopenias dependence discern dysplasia entity extramedullary extrapolation focuses granulocyte hematologic identifies landscape macrophage makes malignancy monocytosis myelomonocytic ontology propensity scientific speculative supporting tools troublesome
Tagcloud (Intersection) ?