GEMIN2 and STXBP2

Number of citations of the paper that reports this interaction (PMID 11748230)
40

Data Source:
HPRD (in vivo)

		GEMIN2	STXBP2
Gene Name		gem (nuclear organelle) associated protein 2	syntaxin binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Cytosol Plasma Membrane SNARE Complex Specific Granule Azurophil Granule Cytolytic Granule Extracellular Vesicular Exosome Tertiary Granule
	Molecular Function	Protein Binding	Protein Binding Syntaxin-3 Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Gene Expression NcRNA Metabolic Process	Leukocyte Mediated Cytotoxicity Vesicle Docking Involved In Exocytosis Protein Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation
Pathways		snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: DDX20 DHX9 GEMIN5 IKBKG RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	13 interactors: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		8487	6813
HPRD ID		03999	03423
Ensembl ID		ENSG00000092208	ENSG00000076944
Uniprot IDs		O14893	B4E175 E7EQD5 Q15833 Q53GF4
PDB IDs		2LEH 3S6N
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression DNA-templated Transcription, Termination MRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Cellular Nitrogen Compound Metabolic Process RNA Export From Nucleus Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport NcRNA Metabolic Process RNA Transport RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Transcription From RNA Polymerase II Promoter Establishment Of Localization In Cell Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Neutrophil Mediated Immunity Neutrophil Activation Cytoplasmic Transport Cellular Localization Positive Regulation Of RNA Splicing Leukocyte Degranulation Regulation Of MRNA Stability Regulated Secretory Pathway	Spliceosomal SnRNP Assembly Ribonucleoprotein Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Cellular Component Assembly Synaptic Vesicle Exocytosis Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Macromolecular Complex Assembly Organelle Fusion MRNA Processing NcRNA Metabolic Process Neurotransmitter Secretion Synaptic Vesicle Transport MRNA Metabolic Process Membrane Fusion RNA Processing Regulation Of Neurotransmitter Levels Exocytosis Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Vesicle Docking Secretion By Cell Membrane Docking Secretion Establishment Of Organelle Localization Leukocyte Degranulation Calcium Ion-dependent Exocytosis Organelle Localization Membrane Organization Regulated Secretory Pathway Cell-cell Signaling Spliceosomal Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Protein Transport Vesicle-mediated Transport Histone MRNA Metabolic Process Establishment Of Protein Localization Regulation Of Exocytosis Leukocyte Activation Involved In Immune Response Glutamate Secretion Termination Of RNA Polymerase II Transcription Protein Localization Long-term Synaptic Potentiation Establishment Of Localization In Cell
Tagcloud ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Difference) ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Intersection) ?