GEMIN2 and SNRPD1

Number of citations of the paper that reports this interaction (PMID 11389857)
82

Data Source:
HPRD (in vitro, in vivo)

		GEMIN2	SNRPD1
Gene Name		gem (nuclear organelle) associated protein 2	small nuclear ribonucleoprotein D1 polypeptide 16kDa
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies	Nucleus Nucleoplasm U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Gene Expression NcRNA Metabolic Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways		snRNP Assembly Metabolism of non-coding RNA	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing snRNP Assembly mRNA Splicing - Minor Pathway Metabolism of non-coding RNA mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: DDX20 DHX9 GEMIN5 IKBKG RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	16 interactors: CLNS1A DDX20 GEMIN2 GEMIN4 GEMIN5 IL7R LSM3 LSM8 PRMT5 SMN1 SMN2 SNRPB SNRPD2 SREK1 U2AF1 WDR77
Entrez ID		8487	6632
HPRD ID		03999	03040
Ensembl ID		ENSG00000092208	ENSG00000167088
Uniprot IDs		O14893	P62314
PDB IDs		2LEH 3S6N	1B34 1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression DNA-templated Transcription, Termination MRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Cellular Nitrogen Compound Metabolic Process RNA Export From Nucleus Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport NcRNA Metabolic Process RNA Transport RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Transcription From RNA Polymerase II Promoter Establishment Of Localization In Cell Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Neutrophil Mediated Immunity Neutrophil Activation Cytoplasmic Transport Cellular Localization Positive Regulation Of RNA Splicing Leukocyte Degranulation Regulation Of MRNA Stability Regulated Secretory Pathway	Spliceosomal SnRNP Assembly RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process Cellular Macromolecular Complex Assembly RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Cellular Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Interleukin-7-mediated Signaling Pathway Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Metabolic Process RNA 3'-end Processing Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of T Cell Mediated Cytotoxicity Histone H4-R3 Methylation Endothelial Cell Activation Cellular Process Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Spliceosomal Tri-snRNP Complex Assembly Lymph Node Development
Tagcloud ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Difference) ?		associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Intersection) ?