SPSB2 and PAWR

Number of citations of the paper that reports this interaction (PMID 20561531)
9

Data Source:
BioGRID (unspecified method)

		SPSB2	PAWR
Gene Name		splA/ryanodine receptor domain and SOCS box containing 2	PRKC, apoptosis, WT1, regulator
Image
Gene Ontology Annotations	Cellular Component	Cellular_component Cytoplasm	Nucleus Cytoplasm Actin Filament Plasma Membrane Actin Cytoskeleton
	Molecular Function	Molecular_function Protein Binding	Transcription Corepressor Activity Actin Binding Protein Binding Enzyme Binding Leucine Zipper Domain Binding
	Biological Process	Biological_process Protein Ubiquitination Intracellular Signal Transduction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Proliferation Negative Regulation Of B Cell Proliferation Interleukin-2 Biosynthetic Process Negative Regulation Of T Cell Proliferation Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Apoptotic Process Negative Regulation Of T Cell Receptor Signaling Pathway Actin Filament Bundle Assembly Apoptotic Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions		6 interactors: APP DDX4 GALNT15 NOS2 PAWR PRMT1	17 interactors: AATF ATP5C1 DAPK3 DRD2 FBXO45 HSPA5 PML PRKCZ RRAS2 SLC5A7 SPSB1 SPSB2 SPSB4 SQSTM1 TFPT THAP1 WT1
Entrez ID		84727	5074
HPRD ID		13610	09051
Ensembl ID		ENSG00000111671
Uniprot IDs		B7Z4W1 Q99619	Q96IZ0
PDB IDs		3EMW	2JK9
Enriched GO Terms of Interacting Partners?		Sexual Reproduction Reproduction Reproductive Process Spermatogenesis Male Gamete Generation Gamete Generation Cell Development Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Synaptic Growth At Neuromuscular Junction Negative Regulation Of Cell Differentiation Collateral Sprouting In Absence Of Injury Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Negative Regulation Of Megakaryocyte Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Peptidyl-cysteine S-nitrosylation Interleukin-2 Biosynthetic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Germ-line Stem Cell Maintenance Axon Choice Point Recognition Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Amyloid Precursor Protein Biosynthetic Process Regulation Of Translation Interleukin-2 Production Arginine Catabolic Process Single Organism Reproductive Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Neuron Remodeling Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Positive Regulation Of Guanylate Cyclase Activity Regulation Of Immune System Process Peptidyl-arginine N-methylation Regulation Of Cellular Respiration Developmental Process Protein Metabolic Process Histone H4-R3 Methylation Positive Regulation Of Glycoprotein Biosynthetic Process Negative Regulation Of Immune System Process Nitric Oxide Biosynthetic Process Organelle Organization Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Glycoprotein Metabolic Process RNA Metabolic Process Cellular Protein Modification Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of B Cell Proliferation Innate Immune Response In Mucosa Histone Arginine Methylation	Regulation Of Cell Death Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Cell Death Apoptotic Signaling Pathway Cellular Response To Stimulus Signaling Cell Communication Signal Transduction Negative Regulation Of Translation Apoptotic Process Programmed Cell Death Regulation Of Protein Metabolic Process Cell Death Death Response To Stimulus Cellular Metabolic Process Response To Organic Substance Cellular Response To Organic Substance Regulation Of Mitotic Cell Cycle Response To Stress Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Long-term Memory Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Response To Interleukin-4 Cellular Response To Stress Negative Regulation Of Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Response To Interleukin-4 Protein Ubiquitination Cellular Response To Growth Factor Stimulus Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Cell Migration Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Morphogenesis Of A Branching Structure Response To Growth Factor Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Translation In Response To Oxidative Stress
Tagcloud ?			aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital
Tagcloud (Difference) ?			aggravating airway airways asthma asthmatic ats cawr coexisting expiratory fev1 forced fvc gastroesophageal gerd hz impulse ios ninety oscillometry pef plethysmography presences reflux representative sec severity tawr verified vital
Tagcloud (Intersection) ?